Effects of Lurasidone on Left Ventricle Systolic Functions
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorAydin Adnan Menderes University
About this trial
The goal of our study to learn if lurasidone molecule which is used on patients with schizophrenia or bipolar disorder has any cardiotoxic effect.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Aged 18 to 65 years
Diagnosed with schizophrenia or bipolar disorder by the psychiatry clinic of our center and indicated to use lurasidone molecule
Hasn't been diagnosed with coronary artery disease, any kind of heart failure or severe valvular disease
Disqualifiers
Patients who do not agree to participate to the trial
Patient who do not meet the inclusion criteria
Trial population
Patients who apply to Adnan Menderes University Psychiatry Clinic and meet the criteria of inclusion
Trial design
Design model
Other
Time perspective
Prospective
Treatments tested in this trial
Global Longitudinal Strain
Diagnostic testGlobal longitudinal strain measurement is a more objective method to determine left ventricular systolic function than traditional eyeballing method. It helps to detect and quantify subtle changes even so it is an emerging method to evaluate the cardiotoxicity of chemotherapeutic drugs. It is planned to compare each selected patient's GLS measurement before starting to use lurasidone and after six months of using it. Hereby our aim is to find if lurasidone has any effect on left ventricular systolic function.
Treatment groups
62 Participants
are divided into 1 treatment groupGroup A: Patients on Lurasidone1 intervention
Trial outcomes
Primary outcomes
1
Lurasidone molecule will affect left ventricular systolic function
We will measure left ventricular global longitudinal strain of each selected patient before starting to use lurasidone and perform the same evaluation for every patient six months later. Since global longitudinal strain measurement is a preferred way to detect subtle changes of wall motions and contractile functions, we will be able detect if this molecule has any negative effect on left ventricular systolic function.
Time frame
All patients whom are admitted by our psychiatry clinic for the next 6 months will be included.Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: