Effects of Miricell Supplementation on Biomarkers of Healthy Aging and Autophagy

ConditionsAutophagy Healthy Aging

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age40-70

SponsorNutraland USA, Inc.

About this trial

The goal of this clinical trial is to learn if a dietary supplement called Miricell works to improve cellular health and signs of healthy aging in adults. It will also learn about the safety of Miricell.

The main questions it aims to answer are:

* Does Miricell improve markers of autophagy, which is the body's natural process for recycling damaged cells? * Does Miricell support brain health, metabolic health, and visible signs of aging? * What medical problems, if any, do participants experience while taking Miricell?

Researchers will compare Miricell to a placebo (a look-alike capsule that contains no active ingredients) to see if Miricell works better to support healthy aging.

Participants will:

* Take either one Miricell capsule or a placebo every day for 12 weeks with a morning meal. * Visit the research clinic four times over the course of the study for checkups and tests. * Complete memory and thinking tests, track their daily physical activity, and give blood samples to measure health changes.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Provide voluntary signed and dated informed consent.

Be in fair health as determined by medical history and routine blood chemistries.

Age between the ages of 40 and 70 (inclusive).

Body weight of at least 110 pounds.

Disqualifiers

Use of probiotics, postbiotics or antibiotics within the past month.

A history of unstable or new-onset cardiovascular/cardiorespiratory, liver, or renal disease.

The participant's alcohol consumption is more than two standard alcoholic drinks per day or more than 10 drinks per week or has a history of drug/alcohol abuse or dependence.

History of diabetes (any form) or any endocrine disorder.

Trial design

Design model

Parallel

Treatments tested in this trial

Spermidine
Dietary supplement
Branded spermidine ingredient (Miricell® Rice Germ Extract) administered orally at a dose of 3.3 mg/day. Provided as a single opaque capsule to be ingested daily with water in the morning with a meal.
Placebo
Dietary supplement
Placebo capsule (microcrystalline cellulose) packaged in an identical-looking, opaque capsule to be ingested daily with water in the morning with a meal.

Treatment groups

70 Participants

are divided into 2 treatment groups

Group A: Miricell™Active comparator 1 intervention

Group B: PlaceboPlacebo comparator 1 intervention

Trial outcomes