The purpose of this research study is to compare muscle activation, changes in pain sensitivity, and brain function, between different walking conditions, including walking to music, walking to metronome, and walking without music or metronome.
Have activity related pain
Experience morning knee stiffness ≤ 30 minutes
Knee pain on most days for 3 months or more
Able to walk at least 20 minutes with assistance
Contraindications to exercise
Joint replacement in either hip, knee, or ankle
History of other disease that may involve the index joint including inflammatory joint disease such as rheumatoid arthritis, seronegative spondyloarthropathy (eg, ankylosing spondylitis, psoriatic arthritis, inflammatory bowel disease related arthropathy), crystalline disease (eg, gout or pseudogout), lupus erythematosus, knee joint infections, Paget's disease affecting the knee, or knee joint tumors.
Previous knee osteotomy in either knee
Single group
Rhythmic Auditory Stimulation with music
BehavioralWalking to rhythmic Auditory Stimulation with music
Rhythmic Auditory Stimulation with metronome
Behavioralwalking to rhythmic Auditory Stimulation with metronome
Control
BehavioralWalking to no music or metronome
Exercise-Induced Hypoalgesia (EIH)
Change in pressure pain threshold (PPT) from baseline to after each walking task
medial quadriceps - medial hamstrings muscle coactivation
Medial quadriceps-medial hamstrings muscle co-activation in each walking task will be assessed using surface electromyography
Medial quadriceps- medial gastrocnemius muscle coactivation
Medial quadriceps-medial gastrocnemius muscle co-activation in each walking task will be assessed using surface electromyography
lateral quadriceps- lateral hamstrings muscle coactivation
Lateral quadriceps-lateral hamstrings muscle co-activation in each walking task will be assessed using surface electromyography
lateral quadriceps - lateral gastrocnemius muscle coactivation
Lateral quadriceps-lateral gastrocnemoius muscle co-activation in each walking task will be assessed using surface electromyography
Prefrontal cortex activation
Prefrontal cortex (PFC) brain activation during each walking task will be assessed using functional near-infrared spectroscopy (fNIRS)
Supplementary Motor Area activation
Supplementary Motor Area (SMA) brain activation during each walking task will be assessed using functional near-infrared spectroscopy (fNIRS)
Auditory-motor synchronization
difference between actual cadence and target cadence in each walking ask (except walking to no music or metronome)
physical activity enjoyment
Modified Physical Activity Enjoyment Scale (PACES) score after each walking task. Range is 7-49 with higher scores indicating greater enjoyment.
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options:
