About this trial
All patients undergoing an implantation of a durable left ventricular assist device and monitored by pulmonary artery catheter showing no adverse events after surgery are included in the study and ventilated for 15 minutes using extra thoracic negative pressure ventilation and usual intrathoracic positive pressure ventilation. Hemodynamics changes between both ventilation modes, especially focussing on right ventricular function and measured by a pulmonary artery catheter, are compared.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
All patients after implantation of a durable left ventricular assist device
Disqualifiers
Complication during surgery like bleeding, emergency, inability to fit the cuirass, unavailability of an investigator, unstable condition regarding circulation or ventilation
Trial design
Crossover
Treatments tested in this trial
Negative pressure ventilation
DeviceAll participants are ventilated with negative pressure ventilation first
positive pressure ventilation
DeviceAll participants are ventilated using positive pressure ventilation after negative pressure ventilation
Treatment groups
Trial outcomes
Primary outcomes
RVSWI
right ventricular stroke work index
Sponsors and contacts
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Karlsburg Hospital
Lead sponsor
University Hospital Freiburg
Collaborator