Effects of Obesity on Physical Abilities and Daily Living Activities in Elderly Adults

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65+
SponsorIstituto Auxologico Italiano

About this trial

Obesity is a significant health problem whose prevalence has tripled worldwide in the last fifty years, also involving older people. Older people present sarcopenia, characterized by the progressive loss of muscle mass and strength. Sarcopenia, accompanied by an increase in adipose tissue, causes a specific condition called sarcopenic obesity. The increase in adipose tissue and the decrease in muscle mass determines a reduction in strength and physical abilities necessary to perform everyday activities of daily living in obese older people.

To understand how the condition of excess adipose tissue influences the activities of daily living of older people with obesity, it is necessary to compare the physical abilities, body composition, and results of various motor skills with normal-weight subjects, corrected for sex and age.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Both sexes

Body Mass Index > 35 kg/m2

Age > 65 years

Hospitalized for a 3-week integrated metabolic rehabilitation program

Disqualifiers

Absence of signed informed consent

Both sexes

Body Mass Index 20-25 kg/m2

Age > 65 years

Trial population

Hospitalized obese elderly following a 3-week integrated metabolic rehabilitation program \+ Normal weight elderly attending correct lifestyle program in their home town

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Fitness tests and questionnaires

    Other intervention

    Anthropometric measurements, physical fitness tests and daily life questionnaires

Treatment groups

160 Participants
are divided into 2 treatment groups
Group A: Obese elderly1 intervention
Group B: Normal weight elderly1 intervention

Trial outcomes

Primary outcomes

1

Fat mass

Fat mass as assessed by bioelectrical impedance

Time frame
Baseline
2

Lean mass

Lean mass as assessed by bioelectrical impedance

Time frame
Baseline
3

Barthel Index

Level of independence in 10 basic daily activities (ADLs) Total score ranges from 0 to 100

Time frame
Baseline
4

Handgrip test

Score in kilograms (kg) using a hand dynamometer

Time frame
Baseline

Secondary outcomes

Other outcomes

Sponsors and contacts

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