Effects of Oral Propranolol on Induction-Delivery Interval During Induction of Labour With Oxytocin

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age15-45
SponsorFederal Teaching Hospital Abakaliki

About this trial

Prolonged pregnancy could lead to perinatal and maternal complications. Oxytocin has been wildly used for induction of labour, but prolonged labour continued to occur with its attendant sequelae. Propranolol, a non-selective B-adrenergic inhibitor has been found to facilitate labour progress in some studies, by the blockade of the effects of catecholamines on the uterus though there are conflicting reports, with the only meta-analysis inconclusive due to few studies used; hence, the need to further study its role in induction of labour. The aim of this study is to assess the role of oral Propranolol in decreasing the induction-delivery with oxytocin

Eligibility criteria

Qualifiers

singleton foetus

cephalic presentation at term

Disqualifiers

Patients on beta blockers

Contraindications to labour or vaginal delivery

Multiple gestations

Preterm labour

Trial design

Treatments tested in this trial

  • Propranolol
  • Placebo

Treatment groups

308 Participants
are divided into 2 treatment groups