Effects of Orofascial Myofunctional Therapy and Cervical Stabilization Exercises on Temporomandibular Dysfunction

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-35
SponsorLahore University of Biological and Applied Sciences

About this trial

Temporomandibular disorders (TMDs) are among the most common musculoskeletal conditions affecting the craniofacial region and are characterized by pain, joint sounds, restricted movement, and functional limitations. Anterior disc displacement is one of the most frequently observed temporomandibular joint (TMJ) disorders and is classified as anterior disc displacement with reduction (ADDwR) or without reduction (ADDwoR). In ADDwR, the articular disc becomes displaced during mandibular movement but returns to its normal position during opening, commonly producing a clicking sound. Although disc displacement can occur in asymptomatic individuals, repeated episodes may interfere with normal joint mechanics, alter mandibular movement, and contribute to maladaptive muscular activity. In some patients, ADDwR may progress to disc displacement without reduction, resulting in limited mouth opening, restricted lateral movement, minimal condylar translation, and deviation of the mandible toward the affected side. TMDs have a multifactorial etiology involving trauma, parafunctional activities such as clenching and bruxism, emotional stress, anxiety, depression, sleep disturbances, abnormal muscle recruitment, occlusal characteristics, and disc or bony morphology. Epidemiological evidence indicates that TMDs are particularly common among adults aged 18-60 years, with a consistent female predominance. Individuals exposed to repetitive masticatory activities and high-stress occupations may also be at increased risk.

Normal orofacial function depends on coordinated activation of the jaw, tongue, lips, cheeks, palate, pharyngeal, and laryngeal muscles. Orofacial Myofunctional Therapy (OMT) consists of individualized oral and peri-oral exercises designed to retrain muscle function and improve the coordination of the stomatognathic system. OMT may promote appropriate tongue posture, nasal breathing, lip seal, swallowing, mastication, and jaw-muscle coordination. Although OMT has demonstrated benefits in several orofacial conditions, its specific role in TMD, particularly ADDwR, remains insufficiently explored. The TMJ also has a close anatomical and neurophysiological relationship with the cervical spine. Cervical muscles contribute to head stabilization during chewing, swallowing, speaking, and breathing, while convergence between trigeminal and cervical sensory pathways can facilitate pain referral between the neck and craniofacial region. Consequently, cervical postural abnormalities, instability, and impaired neuromuscular control may contribute to mandibular dysfunction and TMJ-related pain. Cervical stabilization exercises (CSE) may therefore complement OMT by improving deep cervical muscle activation, reducing excessive superficial muscle activity, and enhancing overall neuromuscular control.

Current research suggests that OMT may improve pain, oral function, muscle activity, and other functional outcomes; however, the evidence remains inconclusive because many studies involve heterogeneous TMD populations, small samples, methodological limitations, combined interventions, and potential placebo effects. Most previous research has also failed to focus specifically on joint-level characteristics such as disc position, reduction mechanics, and condylar-disc coordination. Therefore, a diagnostically precise investigation of patients with ADDwR is warranted. Examining OMT combined with cervical stabilization may provide a more comprehensive rehabilitation approach by addressing both local orofacial dysfunction and associated cervical impairments. Such an integrated intervention could improve mandibular function, muscle coordination, pain, and overall TMJ-related disability. Further high-quality research is therefore needed to establish the effectiveness of combined OMT and cervical stabilization specifically in patients with ADDwR and to guide evidence-based, outcome-oriented management of this common condition.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

All genders

Aged between 18-35 years

Intra-articular, anterior disc displacement with reduction of TMJ, based on RDC/TMD criteria

Axis-I, group II - Disc displacement with reduction

Disqualifiers

Severe systemic conditions affecting muscles or joints (e.g., rheumatoid arthritis, fibromyalgia, generalized joint hypermobility, neuromuscular disorders).

Any psychiatric or neurological disorders interfering with adherence (e.g., uncontrolled epilepsy, major psychiatric illness such as anxiety, stress, or depression).

Previous TMJ surgery, arthroscopy, arthrocentesis, or injection therapy in the past 6 months.

Ongoing dental appliance therapy (splints/braces) unless stabilized for at least 3 months.

Trial design

Design model

Parallel

Treatments tested in this trial

  • orofacial myofunctional therapy

    Other intervention

    Orofacial Myofunctional Therapy (OMT) targets the muscles involved in mastication, mandibular movement, tongue posture, swallowing, lip closure, and overall orofacial coordination. In patients with temporomandibular disorders (TMD), OMT primarily aims to normalize muscle activity, improve neuromuscular coordination, and restore efficient mandibular function rather than directly repositioning the displaced articular disc. The major muscles involved include the masseter, temporalis, medial pterygoid, and lateral pterygoid, which are responsible for mandibular elevation, stabilization, protrusion, and lateral movements. Exercises involving controlled jaw opening, closing, protrusion, and lateral movements may improve coordination and reduce abnormal recruitment of these muscles.Thesuprahyoid muscles, including the digastric, mylohyoid, and geniohyoid, are also targeted through controlled jaw-opening, tongue, and swallowing exercises to improve mandibular dysfunction

  • cervical stabilization exercises

    Other intervention

    Cervical stabilization exercises (CSE) are designed to improve cervical muscle strength, endurance, posture, and neuromuscular control. They are relevant in temporomandibular dysfunction (TMD) because the cervical spine and temporomandibular joint (TMJ) have a close anatomical and neurophysiological relationship. Poor cervical posture, particularly forward head posture, may alter mandibular positioning and increase abnormal activity of the masticatory and cervical muscles. The main muscles targeted by CSE are the deep cervical flexors, especially the longus colli and longus capitis, along with the cervical multifidus. The suboccipital muscles also contribute to head positioning and proprioception. CSE aims to activate these deep stabilizing muscles while reducing excessive compensatory activity of superficial muscles such as the sternocleidomastoid, anterior scalenes, and upper trapezius. Craniocervical flexion and controlled stabilization exercises can improve cervical alignment.

Treatment groups

80 Participants
are divided into 2 treatment groups
Group A: Orofacial myofunctional therapyExperimental treatment 1 intervention
Group B: cervical stabilization exercisesActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Maximum Mouth Opening

Measuring tape for jaw range of motion (MMO; Opening, Closing, lateral deviation) A measuring tape (or millimeter ruler) is a simple, inexpensive, and commonly used clinical tool to measure jaw range of motion (ROM) in patients with temporomandibular disorders. Itis primarily used to measure maximum mouth opening by recording the distance (inmillimeters) between the upper and lower central incisors during maximal mouth opening. It can also be used to assess lateral excursion and protrusion.

Time frame
12 weeks
2

jaw pain intensity

Numeric Pain rating scale is a numeric pain rating scale. This 11-point scale allows participants to rate their pain level on a scale of 0 to 10, where 0 indicates no pain and ten indicates pain as bad as it can .In this study patients have pain not less than 4-8

Time frame
12 Weeks
3

occlusal load

Maximum relative occlusal load / Right-Left Load Distribution (Occlusense Analysis).Right-left load distribution describes the percentage distribution of occlusal force between the right and left sides of the dental arch during occlusion. It reflects the symmetry or imbalance of bite force across both sides. Right-left load distribution describes the percentage distribution of occlusal force between the right and left sides of the dental arch during occlusion. It reflects the symmetry or imbalance of bite force across both sides.

Time frame
12 weeks
4

Functional limitations

Jaw functional limitation scale (JFLS- 20 items) The Jaw Functional Limitation Scale (JFLS) is a validated patient-reported questionnaire used to assess functional limitations in individuals with temporomandibular disorders. It measures difficulties in jaw-related activities such as chewing, opening the mouth, and verbal or emotional communication. The JFLS is available in 20-item (JFLS-20) and 8-item (JFLS8) versions, with each item scored on an 11-point scale (0-10), where higher scores indicate greater functional limitation.

Time frame
12 weeks

Secondary outcomes

Other outcomes

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