Effects of Partial Sleep Deprivation on Cardiac Output During Cycling
ConditionSleep Deprivation
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorUniversity of Guelph
About this trial
The goal of this clinical trial is to determine if attenuations in cardiac output drive the blunted blood pressure response during cycling exercise following a night of partial sleep deprivation in young healthy adults (%50 females). The secondary outcome is to assess sex differences. The main questions it aims to answer are:
* Do reductions in plasma volume drive reductions in cardiac output and therefore blood pressure during exercise following a night of partial sleep deprivation? * Do sex differences exist?
Participants will:
* Visit the lab after a night of normal sleep and a night of partial sleep deprivation. * Keep a daily diary of their sleep and food/beverage intake. * Perform maximal and submaximal exercise on a cycle ergometer.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Free of known cardiovascular or metabolic diseases or sleep disorders
No history of smoking (within the past 3 months)
Able to engage in physical activity assessed through the physical activity readiness questionnaire (PAR-Q+)
No prescription of chronic medications other than oral contraceptives
Disqualifiers
Individuals diagnosed with cardiovascular or metabolic disease or sleep disorders
Has a history of smoking (within the past 3 months)
Not ready to engage in physical activity as assessed by the PAR-Q+
Individuals prescribed chronic medications other than oral contraceptives
Trial design
Design model
Crossover
Treatments tested in this trial
Partial sleep deprivation
Other interventionParticipants will be asked to come to the lab for testing after a night of partial sleep deprivation. Participants will be asked to fall asleep at their habitual bedtime but wake up early (\~40% of normal sleep duration).
Treatment groups
30 Participants
are divided into 2 treatment groupsGroup A: Normal sleepNo intervention 0 interventions
Group B: Partial sleep deprivationExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
cardiac output responses to cycling exercise
Cardiac output during exercise after a night of normal sleep and after a night of partial sleep deprivation
Time frame
Comparison between normal sleep and partial sleep deprivation, ~3 weeksSecondary outcomes
1
Blood pressure responses to cycling exercise
Blood pressure during exercise after a night of normal sleep and after a night of partial sleep deprivation
Time frame
Comparison between normal sleep and partial sleep deprivation, ~3 weeks2
Plasma volume
Plasma volume after a night of normal sleep and after a night of partial sleep deprivation
Time frame
Comparison between normal sleep and partial sleep deprivation, ~3 weeksSponsors and contacts
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Source ClinicalTrials.gov