About this trial
The goal of this clinical trial is to evaluate the effectiveness of periodontal treatment associated with the use of a tongue scraper, compared with the same treatment combined with antimicrobial photodynamic therapy (aPDT), in reducing halitosis in individuals with periodontal disease and type 2 diabetes mellitus. The main question it aims to answer is: aPDT treatment is more effective in treating halitosis? aPDT treatment is more effective in periodontitis? Researchers will compare aPDT treatment to conventional treatment (scaling and root planning and tongue scraper) to see if aPDT has additional effects in reducing halitosis and improving periodontal health.
* Participants will be asked to visit the clinic once a week for exam and treatment during 1 month. * After active treatment they will be asked to come to maintenance and control visits once a month until 6 months.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients diagnosed with type 2 diabetes mellitus according to the 2019 WHO criteria
Stage 3 or 4 periodontitis
No periodontal treatment in the previous 12 months
a minimum of 20 remaining teeth.
Disqualifiers
Smokers
Alcohol-dependent individuals
Pregnant or lactating women
Patients with renal disorders
Trial design
Parallel
Treatments tested in this trial
Scaling and root planing
Procedure/SurgeryMechanical removal of biofilm in periodontal pockets and tongue
Photodynamic Therapy with Conventional Methylene Blue
Procedure/SurgeryAntimicrobial photodynamic therapy in periodontal pockets and tongue
Treatment groups
Trial outcomes
Primary outcomes
Halitosis
Measurement of oral volatile compounds by gas chromatography
Secondary outcomes
Probing depth
Measurement in milimeters of the periodontal pocket
Clinical Attachment level
Measuremet in milimeters from cementoenamel junction to bottom of the pocket
Sponsors and contacts
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