The study aims to evaluate the effect of the royal jelly and propolis on inflammation and oxidative stress in participants with systemic arterial hypertension. A longitudinal double-blind randomized clinical trial will be carried out, involving hypertensive participants for two months.
Diagnosis of stage 1 and 2 hypertension
Regular treatment for more than 6 months
There have been no changes in medication doses over the last three months.
Autoimmune and infectious diseases, diabetes
Chronic kidney disease, liver disease, cancer and AIDS
Pregnant women
Use of catabolic drugs or antibiotics
Parallel
Placebo
Dietary supplementThe placebo group will receive 4 capsules per day (containing microcrystalline cellulose and magnesium stearate in colored gelatin capsules capable of masking the appearance of the internal content), at the same time for 2 months.
Royal Jelly + Propolis Group
Dietary supplementParticipants will receive 4 capsules per day, providing the dosage of 300mg of royal jelly + 500mg propolis for 2 months (8 weeks).
Change of inflammatory citokynes
Get blood samples to evaluate the supplementation effects in inflammatory cytokines such as interleukin 6 (IL-6, pg/mL), IL-1b (pg/mL), IL-17 (pg/mL) e TNF-α (pg/mL)
Click on the lead sponsor to view all of their trials.
