Effects of Pulmonary Rehabilitation on Quality of Life and Health in Pulmonary Arterial Hypertension Patients

ConditionsPAH CTEPH

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18+

SponsorBeijing Chao Yang Hospital

About this trial

Pulmonary hypertension (PH) is a major global health concern, affecting approximately 1% of the world's population. With global aging and increased life expectancy, its incidence continues to rise. PH is a progressive and disabling disease, with studies showing its progression correlates with worsening symptoms and increased mortality. Even with targeted medications, the prognosis remains poor across PH subtypes, with PAH patients showing only a 49% 7-year survival rate. The 2022 ESC/ERS guidelines emphasize that PH management requires a comprehensive, multidisciplinary approach. Beyond pharmacological and surgical treatments, rehabilitation has demonstrated benefits in improving exercise capacity, quality of life, functional class, and peak oxygen consumption. However, research on specific and effective comprehensive pulmonary rehabilitation programs remains lacking.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Group 1 (PAH) or

Group 4 (CTEPH/other pulmonary artery obstructions)

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

Comprehensive Pulmonary Rehabilitation Program
Behavioral
Combined Aerobic + Resistance Training Program Mode: Cycle ergometry (stationary bicycle) Frequency: 3-5 sessions per week Program Duration: 12 weeks Session Structure: * 5-minute warm-up * Continuous or interval training (15-30 minutes) * 5-minute cool-downesistance Exercise Component Mode: Dumbbell exercises + cycle ergometry Frequency: 3 sessions per week Program Duration: 12 weeks Session Structure: * 5-minute warm-up * Training session (10-20 minutes) * 5-minute cool-down
Standard Pulmonary Rehabilitation
Behavioral
xercise Components: Aerobic Exercise Mode: Walking or jogging Resistance Exercise Mode: Elastic bands or dumbbells Training Parameters: Session Duration: ≥35 minutes (combined aerobic + resistance) Frequency: 3-5 sessions per week Program Duration: 12 weeks

Treatment groups

84 Participants

are divided into 2 treatment groups

Group A: Comprehensive Pulmonary Rehabilitation ProgramExperimental treatment 1 intervention

Group B: Standard Pulmonary RehabilitationActive comparator 1 intervention

Trial outcomes

Primary outcomes

6MWD

Time frame

12week

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Beijing Chao Yang Hospital

Lead sponsor

Beijing Municipal Health Commission

Collaborator

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: