The goal of this observational study is to explore the effect of remimazolam-based total intravenous anesthesia on postoperative neurocognitive function in patients who undergo cardiovascular surgery.
The main question this study tries to answer is: Does remimazolam influence the incidence of postoperative delirium in cardiovascular surgery? Participants already apply remimazolam-based total intravenous anesthesia as part of their regular medical treatment for general anesthesia to perform cardiac surgery will answer questionnaires about cognitive function after surgery.
Male or female adult patients aged 60 years or older
Receiving elective cardiovascular surgery with cardiopulmonary bypass
Written Informed consent provided
Deep hypothermia circulatory arrest
Breastfeeding or pregnancy
Mental or legal disability
Terminal illness with a life expectancy of less than 3 months
Undergo elective cardiovascular surgery with cardiopulmonary bypass
Cohort
Prospective
Not listed
the 5-day incidence of postoperative delirium
the incedence of delirium evaluated by CAM/CAM-ICU
Time to extubation
Time to extubation postoperatively
Length of stay (LOS) in intensive care unit (ICU)
Length of stay (LOS) in intensive care unit (ICU) postoperatively
Length of stay (LOS) in hospital
Length of stay (LOS) in hospital postoperatively
the 30-day composite incidence of major adverse events
Major adverse events refer to transient ischemic attack, stroke, renal insufficiency, myocardial infarction, pulmonary embolism, seizure and all-cause mortality.
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