Effects of Stereotype Threat on Impulsivity and Its Relation to Alcohol Use in African Americans: An fMRI Study

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-35
SponsorIcahn School of Medicine at Mount Sinai

About this trial

The purpose of this study is to investigate the behavioral and neural correlates of stress exposure. Results from this study will enrich the understanding of how sociocultural, behavioral, and neural factors combine to influence alcohol use.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Between 21 and 35 years of age (inclusive);

Fluent in English;

Right-handed

Disqualifiers

Younger than 21 years of age;

Left-handed

Trial design

Design model

Parallel

Treatments tested in this trial

  • Task-based behavioral intervention

    Behavioral

    Brief behavioral intervention is absent of stressors.

  • Task-based behavioral intervention

    Behavioral

    Brief behavioral intervention involves interacting with common everyday types of stress.

Treatment groups

280 Participants
are divided into 2 treatment groups
Group A: no stress exposurePlacebo comparator 1 intervention
Group B: stress exposureActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Blood oxygen-level dependent (BOLD) signal

Blood oxygen-level dependent (BOLD) signal in brain regions of interest (ROI) measured using fMRI

Time frame
Baseline
2

Resting-state functional connectivity in brain regions

Resting-state functional connectivity - brain activity measured using fMRI

Time frame
Baseline

Secondary outcomes

Other outcomes

Sponsors and contacts

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Icahn School of Medicine at Mount Sinai

Lead sponsor

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Collaborator