Effects of Therapeutic Exercise With and Without Nerve Stimulation on Dysphonia in Post Thyroidectomy Patients

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorUniversity of Lahore

About this trial

This clinical trial evaluates rehabilitation strategies for post-thyroidectomy dysphonia. Voice impairment is a frequent complication following thyroid surgery. It often occurs even without direct laryngeal nerve transection. Surgical trauma, tissue edema, and mechanical stretching of the laryngeal nerves or surrounding musculature can cause persistent voice changes. These changes significantly lower a patient's quality of life.This study compares two distinct interventions against standard care:Therapeutic Voice and Neck Exercise AloneTherapeutic Voice and Neck Exercise Combined with Transcutaneous Electrical Nerve Stimulation (TENS)The objective is to determine if adding non-invasive nerve stimulation to standard therapeutic exercises accelerates neuromuscular recovery, improves vocal fold mobility, and enhances overall voice quality more effectively than exercise alone. Background and Rationale Thyroidectomies are common surgical procedures worldwide. Dysphonia post-surgery stems from multiple factors. These include temporary or permanent recurrent laryngeal nerve (RLN) neuropraxia, external branch of the superior laryngeal nerve (EBSLN) injury, laryngotracheal fixation, and peri laryngeal scarring. Patients frequently report hoarseness, vocal fatigue, reduced pitch range, and breathiness. Standard management typically includes watchful waiting or traditional voice therapy. Therapeutic exercises aim to stretch scarred tissues, strengthen paretic intrinsic laryngeal muscles, and optimize respiratory support. Transcutaneous Electrical Nerve Stimulation (TENS) uses low-voltage electrical currents to stimulate peripheral nerves. TENS is hypothesized to reduce local pain, increase regional blood flow, decrease muscle tension, and facilitate neural regeneration when applied to the anterior neck. By combining these therapies, this trial investigates whether sensory and motor electrical stimulation acts synergistically with active physical and vocal exercises. The goal is to provide a superior, faster recovery pathway for patients suffering from post-operative voice disorders.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

age 18 to 60 years 2. diagnosed with dysphonia 3. able to attend 3 sessions per week for 6 weeks -

Disqualifiers

history of laryngeal surgery 2. neurological disorder affecting voice 3. pregnancy

Trial design

Design model

Parallel

Treatments tested in this trial

  • therapeutic exercise

    Behavioral

    voice therapy exercise including vocal hygiene , resonance exercise, and breathing exercise. 3 sessions per week for 6 weeks , 45 min each session

  • therapeutic exercise + transcutaneous nerve stimulation

    Behavioral

    voice therapy exercise plus transcutaneous nerve stimulation applied to laryngeal area . 3 sessions per week for 6 weeks 45 minutes each session

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: voice therapy only groupExperimental treatment 1 intervention
Group B: voice therapy + TENS groupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

voice handicap index -10 score

change in VHI-10 score from baseline to 6 weeks to assess severity of dysphonia

Time frame
baseline and 6 weeks post intervention

Secondary outcomes

1

Maximum phonation time

change in MPT in second from baseline to 6 weeks

Time frame
baseline and 6 weeks post intervention

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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