Effects of Total and Selective Caries Removal - Requiring or Avoiding Vital Pulp Therapy - on Pulp Vitality and Postoperative Pain in Deep Carious Mature Permanent Teeth: A Split-Mouth Clinical Study

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age15-55
SponsorCukurova University

About this trial

The effect of selective caries cleaning and total caries cleaning on pulp health and post operative pain in teeth with deep caries will be investigated.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients aged ≥15 years with bilateral deep carious mature permanent teeth.

Positive vitality test (cold sensitivity).

No spontaneous pain or periapical radiolucency.

Willingness to attend 6- and 12-month follow-ups

Disqualifiers

Uncontrolled systemic diseases Pregnancy or allergy to dental materials used Teeth with irreversible pulpitis (spontaneous pain, necrosis) Non-restorable teeth (fractures, extensive decay)

Trial design

Design model

Crossover

Treatments tested in this trial

  • Total Caries Removal

    Procedure/Surgery

    Arm 1: "Total caries removal (complete excavation to hard dentin)"

  • Selective Caries Removal

    Procedure/Surgery

    Partial removal leaving affected dentin near pulp.

Treatment groups

15 Participants
are divided into 2 treatment groups
Group A: Arm 1Active comparator 1 intervention
Group B: Arm 2Experimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Early postoperative pain intensity (VAS) after total vs. selective excavation

The patient will be asked to rate his/her pain on day 1, 3 and 7 according to VAS

Time frame
first week
2

dentin bridge formation

no dentin bridge formation is expected in selective caries cleaning, while dentin bridge formation will be observed radiologically in total cleaning

Time frame
twelve months
3

pulp survival at twelve months

The pulp is expected to remain vital, with no percussion tenderness and no spontaneous pain

Time frame
twelve months

Secondary outcomes

Other outcomes

Sponsors and contacts

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