Health TrialsbyHealthPanel

Effects of Walking Apnea At High Lung Volume on Hypoalgesia

ConditionsPainHypoxemiaHypercapniaApnea
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorUniversidad Rey Juan Carlos

About this trial

The aim of this randomized controlled study is to explore the hypoalgesic response of a 6 minutes of intermittent walking apneas training session at high lung volume in healthy subjects; also, as secondary objectives, to analyze the cardiovascular and respiratory response produced during the intervention.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Asymptomatic subjects aged between 18 and 64 years.

Disqualifiers

Cardiovascular, respiratory, metabolic, neurological or osteomuscular signs or pathologies.

History of epilepsy.

Pregnant

Pharmacological treatment.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Walking apnea at High Lung Volume

    Other intervention

    Walking apnea at High Lung Volume Participants walk at 6 km/h (10% slope) on treadmill for 6 minutes. Participants in the experimental group will perform intermittent apneas at high lung volume with a density of 5 seconds, followed by a normal breath of 5 seconds until completing the 6 minutes)

  • Walking normal breathing

    Other intervention

    Participants walk at 6 km/h (10% slope) on treadmill for 6 minutes. Participants in the control group will remain breathing normally for these 6 minutes.

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: Walking apneaExperimental treatment 1 intervention
Group B: Walking normal breathingActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Pain pressure threshold (PPT) on thumb, anterior tibial and spinous process of C7

PPT is tested on the dorsal base of the distal phalanx of the thumb on the dominant side and on the muscle belly of the tibialis anterior on the dominant side. The region to be pressed is marked with a pen. The patient is instructed to report with the first appearance of the sensation of "discomfort". An ascending ramp of 0.5 kg/cm/s is applied, at the rhythm of a metronome. The measurement is started on the thumb, and alternated with tibia and C7 until 3 measurements of each region are obtained, enough time to give 30 seconds of rest between measurements in the same region. This protocol has demonstrated high inter observer reliability measuring healthy subjects (ICC = 0.91).

Time frame
before and after intervention (up 30 minutes)

Secondary outcomes

1

Perceived Stress Scale (PSS)

14-item questionnaire about their thoughts and feelings in the last month. The scale has a range of scores from 0 to 56. The lower the score, the more favorable for the patient's health.

Time frame
before intervention (up 5 minutes)
2

Pittsburg Sleep Quality Index (PSQI)

9-item questionnaire on sleep quality in the past month. The scale has a range of scores from 0 to 21. The lower the score, the more favorable for the patient's health.

Time frame
before intervention (up 5 minutes)
3

Global Physical Activity Questionnaire (GPAQ)

6-item questionnaire on the level of physical activity at work, for commuting and in leisure time. A higher score means higher weekly physical activity

Time frame
before intervention (up 5 minutes)
4

Heart rate

Heart rate will be measured during the procedure by finger pulse oximetry.

Time frame
during intervention (up 6 minutes)

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Universidad Rey Juan Carlos

Lead sponsor

Source ClinicalTrials.gov
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