Effects of Zinc Supplementation on Patients With Elevated Glycemic Status

ConditionElevated Blood Glucose

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18+

SponsorZhilei Shan

About this trial

The goal of this randomized, double-blind, placebo-controlled study included patients with elevated glycemic status is to investigate whether zinc supplementation (4mg per day) has beneficial effects on controlling blood glucose.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Fasting blood glucose ≥ 6.1 mmol /L;

HBA1c ≥ 5.7%;

OGTT 2-hour or postprandial blood glucose ≥ 7.8 mmol/L;

Patients with previously diagnosed type 2 diabetes with stable drug hypoglycemic treatment and blood glucose controlled well.

Disqualifiers

Age < 18 years, or currently pregnant;

Individuals with severe obesity, thyroid disease, cardiovascular or cerebrovascular diseases, or other serious health conditions;

Individuals with a previous diagnosis of type 2 diabetes currently receiving insulin therapy;

Individuals who have taken zinc-related supplements within three months prior to baseline inclusion;

Trial design

Design model

Parallel

Treatments tested in this trial

Zinc-enriched yeast capsule
Dietary supplement
Daily zinc supplementation: zinc-enriched yeast capsules (15 mg) for a total of 6 months.
Edible yeast placebo capsule
Dietary supplement
Daily edible yeast placebo capsules (not zinc-enriched) (15 mg) for a total of 6 months.

Treatment groups

124 Participants

are divided into 2 treatment groups

Group A: Zinc supplementationExperimental treatment 1 intervention

Group B: Edible yeast placeboPlacebo comparator 1 intervention

Trial outcomes