About this trial
Efficacy and safety of amphotericin B and azoles in the treatment of invasive fungal disease
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
There is no age limit, gender is not limited
Patients with invasive fungal disease who are treated with polyene antifungals or azole antifungals should be treated for ≥ 7 days.
Disqualifiers
Patients with incomplete data or other factors affecting the clinical outcome judgement
Patients who are judged by the investigator to be unsuitable to participate in this study.
Trial population
Patients with invasive fungal disease who are treated with polyene antifungals or azole antifungals should be treated for ≥ 7 days.
Trial design
Other
Retrospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Clinical success rate
Clinical success incudes cure or symptom improvement,which means patients are alive, IFD-related symptoms and signs, radiographic abnormalities improve or disappear completely, and microbiological evidence suggests fungal clearance. The proportion of patients with cured or improved symptoms in the total population was analyzed.
Secondary outcomes
Safety of amphotericin B and azoles
Safety evaluation was mainly based on the incidence of adverse events / adverse reactions in the two groups of patients.
Sponsors and contacts
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