This is a multi-center, single arm, prospective, open-label, extendable study for the efficacy and safety of combo-stim deep brain stimulation for treatment-refractory mental disorders (obsessive-compulsive disorder, schizophrenia, bipolar with depression, anorexia nervosa, gambling disorder and adult autism).
Aged 18~65 when signing informed consent, outpatient or inpatient, male or female.
Fits DSM-5 obsessive-compulsive disorder criteria.
Aged 18~65 when signing informed consent, outpatient or inpatient, male or female.
Fits DSM-5 schizophrenia criteria.
With mental disorders including physical mental disorders, paranoid personality disorder, delayed mental development etc.
Through clinical evaluation by investigators, there exists significant suicide behavior risk.
Obsessive compulsive disorder: Y-BOCS score decreased (or improved) ≥ 20%
Schizophrenia: PANSS score decreased (or improved) ≥ 20%
Shanghai Mental Health Center
Lead sponsor
SceneRay Corporation, Limited
Collaborator
Huashan Hospital
Collaborator
Shanghai 6th People's Hospital
Collaborator
Changhai Hospital
Collaborator