Efficacy and Safety of Left Bundle Area Pacing Vs Right Ventricular Apical Pacing in Patients with Atrioventricular Block

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorAssiut University

About this trial

This study will address whether LBBaP is superior to RVAP in terms of safety and efficacy

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients with AVB who meet indications for pacemaker

Implantation with an estimated percentage of ventricular pacing ≥50%

Ability to provide informed consent

Disqualifiers

Failure to cooperate with follow-up.

Persistent atrial fibrillation.

Patients with heart failure (LVEF) ≤35%,

Estimated glomerular filtration rate less than 30 ml/min.

Trial population

. Patients with AVB who meet indications for pacemaker , with an estimated percentage of ventricular pacing ≥50%

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

42 Participants
are grouped into 2 trial groups
Group A: LBB area pacing group
Group B: RV apical pacing area

Trial outcomes

Primary outcomes

1

effectiveness with LBB pacing

Assess left ventricular global strain using speckle tracking echocardiography (percentage)

Time frame
3 years
2

Incidence of adverse events in patient with LBB pacing

Malignant arrhythmia(Yes/No)

Time frame
3 years
3

Incidence of septal perforation

Detect septal perforation(Yes/No)

Time frame
3 years

Secondary outcomes

1

Major Adverse Cardiovascular Events

• All-cause mortality (Yes or No) cardiovascular deaths (Yes or No) rehospitalisation with heart failure (Yes or No) Lead dislocation (Yes or No) Lead infection. (Yes or No)

Time frame
3 years

Other outcomes

Sponsors and contacts

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This trial is not recruiting at the moment. You can still explore other options: