Efficacy and Safety of Pulsed Radiofrequency Combined With Platelet Rich Plasma to Treat Idiopathic Glossopharyngeal Neuralgia (GPN)

ConditionsGlossopharyngeal Neuralgia Pulsed Radiofrequency Platelet Rich Plasma

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorBeijing Tiantan Hospital

About this trial

To investigate the efficacy and safety of the application of PRF combined PRP to the for the treatment of GPN.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

age >18 years;

diagnosed with idiopathic GPN according to the third International Classification of Headache Disorders (ICHD) classification;

patients who failed pharmacotherapy or intolerable side effects of medication;

undergoing PRF for GPN;

Disqualifiers

Patients with bilateral GPN;

Abnormalities in blood measurements, liver and kidney function, blood glucose, coagulation, electrocardiography or chest radiography;

Infection at the puncture site;

Previous mental illness;

Trial population

Suitable participants will be screened at the pain management center of each hospital to participate in the study.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

121 Participants

are grouped into 2 trial groups

Group A: PRF group

Group B: PRF+PRP group

Trial outcomes

Primary outcomes

Numeric rating scale (NRS) score

Numeric rating scale (NRS) score during resting was used to evaluate pain intensity before and after PRF treatment (0=no pain, 10=intolerable pain)

Time frame

1day, 3days, 1week, 2weeks, 1month, 3months, 6months, and 1year following the procedure

Secondary outcomes

Barrow Neurological Institute pain scale(BNI score)

BNI score during resting was used to evaluate pain relief

Time frame

1day, 3days, 1week, 2weeks, 1month, 3months, 6months, and 1year following the procedure

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Beijing Tiantan Hospital

Lead sponsor

China-Japan Friendship Hospital

Collaborator

The Second Hospital of Hebei Medical University