Efficacy of Behavioral Therapy for Chronic Refractory Cough
ConditionChronic Cough
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorAssiut University
About this trial
Chronic cough is defined as cough persisting for more than eight weeks. It is a common clinical problem that significantly impairs patients' physical, psychological, and social quality of life. Chronic cough remains a diagnostic and therapeutic challenge despite systematic evaluation and treatment of common etiologies such as asthma, gastroesophageal reflux disease
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Eligible participants are adults aged ≥18 years i.e. normal chest radiograph.
participants with chronic cough persisting for more than eight weeks that is refractory to standard medical treatment for common causes of chronic cough, including asthma, gastroesophageal reflux disease .
Participants are required to exhibit clinical features suggestive of laryngeal hyperresponsiveness, such as cough triggered by phonation, laughter, cold air, or irritant exposure, with associated laryngeal symptoms including throat irritation, dysphonia, or frequent throat clearing.
Disqualifiers
Patients are excluded if they are current smokers or had ceased smoking within six months
patients have evidence of active pulmonary or cardiac disease, recent respiratory tract infection, recent angiotensin-converting enzyme inhibitor use.
significant structural laryngeal pathology, neurological disorders affecting cough reflex control, or inability to comply with study procedures.
Head &neck pathology e.g sinusitis, glottal insufficiency or primary muscle tension dysphonia
Trial design
Design model
Single group
Treatments tested in this trial
Behavioral Therapy
Behavioralto evaluate the efficacy of behavioral therapy for chronic cough in patients with laryngeal hyperresponsiveness in order to assess its role as a non-pharmacological management strategy. This will provide an efficient plan of therapy for such challenging condition.
Treatment groups
30 Participants
are divided into 1 treatment groupGroup A: Behavioral Therapy for chronic coughExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Treatment of Chronic Cough
The patient's subjective response to treatment, categorized as: resolved, improved, no change, or worse. it will be assisted by Cough-Specific Quality of Life: Leicester Cough Questionnaire (LCQ): The primary measure of cough-specific health-related quality of life (QoL). and also assesses physical, psychological, and social domains
Time frame
6 monthsSponsors and contacts
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Source ClinicalTrials.gov