The goal of this clinical trial is to learn if high-level laser therapy can manage oral mucositis in pediatric patients undergoing hematopoietic bone marrow transplantation. The main question it aims to answer is :
Is high-level laser therapy effective as a treatment for oral mucositis in pediatric hemopoietic stem cell transplant patients? Researchers will compare patients receiving basic oral care to see the effect on the WHO oral mucositis scale.
Participants will be subjected to high level laser on lesion sites .
Children under the age of 18 years undergoing bone marrow transplantation during the phase of oral mucositis.
Oral mucositis starting from grade II on the WHO scale for OM.
Willingness to undergo treatment for four consecutive days and to return for evaluation 7 and 11 days after enrolment.
Previous treatment with photobiomodulation for oral mucositis.
Limited mouth opening less than 2 cm.
Presence of dysplastic oral lesions.
Radiotherapy in the head and neck area.
Parallel
high power laser therapy
Devicehigh power laser therapy once daily for four consecutive days with wavelength 660 to 970 nm, power 3.2 w, and duration of 230 seconds at 50% duty cycle
Basic oral care
Drugpatients will receive local methods: cholorohexidine mouthwash as well sodium bicarbonate mouthwash
Oral mucositis score
World Health Organization (WHO) scale of oral mucositis will be used to describe the lesions at baseline, day 7 and day 11, lesions are given grades from 1 to 4, with 4 being a worse outcome
Pain score
Pain visual analogue scale will be used to measure pain level, where the patient will be given a diagram representing pain levels from 1 to 10, 10 being the highest level of pain
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