The Purpose of the study is to evaluate the efficacy of LN18178 in improving muscle strength, aerobic capacity and body composition in healthy young males.
Untrained healthy male subjects aged between 36 and 50 years with a Body Mass Index (BMI) between 22 and 27 kg/m2.
Willingness to do exercise training program during the course of the study.
Subject considered generally healthy as per health history and routine clinical investigations.
Ability to understand the risks and benefits of the protocol.
Subjects who are resistance trained or undergoing resistance training.
Subjects with blood pressure more than or equal to 140/90 mmHg, fasting plasma glucose more than 125 mg/dL and abnormal ECG.
Subjects underwent treatment for COVID-19 within last 3 months or tested positive during the study will be excluded.
Evidence or history of musculoskeletal, respiratory, haematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, neurologic diseases, malignancies.
Parallel
LN18178
Dietary supplement400 mg, One capsule to be consumed in the morning after breakfast with water for 12 Weeks
Placebo
Dietary supplementOne capsule to be consumed in the morning after breakfast with water for 12 Weeks
Change in Muscle strength (1-RM leg press)
It's the maximum amount of weight a subject can lift for one repetition of leg press. As the weight lifted increases, muscle strength also rises
Change in Muscle strength ( 1-RM bench press)
It's the maximum amount of weight a subject can lift for one repetition of bench press. As the weight lifted increases, so does muscle strength.
Change in Muscle endurance (Repetitions to failure for leg press and bench press using 80% 1RM)
It refers to the maximum number of repetitions a person can perform at 80% of their one-repetition maximum (1RM) weight on the leg press and bench press. An increase in repetitions reflects improved muscle endurance.
Change in training volume/capacity
It is a calculated value obtained by multiplying the number of sets, the number of repetitions per set, and the weight lifted in kilograms for an exercise. As training volume increases, so does muscle strength.
Change in VO2 max testing (graded exercise test while O2 consumption measured)
The maximum amount of oxygen the body utilizes during graded exercise on an ergometer is measured as VO₂ max. An increase in VO2 max indicates improved cardiovascular fitness
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