About this trial
Oropharyngeal muscle training has emerged as a novel adjunctive treatment approach, involving training of the swallowing muscle group and tongue muscles to prevent tongue collapse, reduce tongue base volume during sleep, and strengthen muscle tension.
Therefore, the objective is to assess changes in oropharyngeal muscle strength, ultrasonographic tongue morphology, severity of sleep related breathing interruptions, clinical symptoms, and correlations among these factors. Oropharyngeal muscle training for patients with residual OSA using MAD can significantly 1. increase muscle strength and endurance. 2. reduce the severity of sleep-related breathing interruptions. 3. decrease clinical symptoms. 4. improve tongue morphology.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
OSA patients
Aged over 20 years
Wearing MAD (The amount of MAD is at least 50% of the maximum amount that the patient can achieve.)
Disqualifiers
Body Mass Index (BMI) ≧ 35
Pregnancy
Severe obstructive or restrictive lung disease
Exercise with high-risk cardiovascular disease
Trial design
Parallel
Treatments tested in this trial
Oropharyngeal Exercises
Other interventionOropharyngeal Exercises
Mandibular advancement device
Other interventionMandibular advancement device
Treatment groups
Trial outcomes
Primary outcomes
Apnea-hypopnea -index
Assessed using Polysomnography (PSG). The average apnea and hypopnea events per hour, oxygen saturation index and the snoring index will be obtained during the sleep test(PSG).
Secondary outcomes
Tongue muscle strength
The maximal muscle strength of genioglossus muscles using The Iowa Oral Performance Instrument (IOPI) system, model 2.2 (Northwest, Co., LLC, Carnation, WA, USA) (kPa)
Jaw strength
Jaw strength will be measured using a 'handheld' dynamometer (MicroFET○R2, Hoggan Scientific, USA). The data will be presented in kilogram-weight. The minimum score is 0 and a higher score indicates stronger in jaw strength.
Tongue muscle endurance
The endurance of the genioglossus muscles using The Iowa Oral Performance Instrument (IOPI) system, model 2.2 (Northwest, Co., LLC, Carnation, WA, USA) (in seconds).
Tongue Muscle Thickness
Sonography will be performed over the participant's neck region to assess the changes in tongue muscle thickness during normal breathing.
Sponsors and contacts
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