Efficacy Validation of Deep Microspicule Cream for Anti-aging and Whitening on Mature Skin

ConditionEfficacy Validation of Deep Microspicule Cream for Anti-aging and Whitening on Mature Skin

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age40-65

SponsorChung Shan Medical University

About this trial

This study is a single-center, prospective, split-face self-controlled pilot trial designed to evaluate the anti-aging and whitening efficacy of the "Deep Microspicule Cream" (containing patented crystal microspicules encapsulating Penghu seaweed extract) on mature skin.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Healthy male or female participants aged 40-65 years.

Presence of at least one facial aging or hyperpigmentation feature (e.g., eye area sagging, eye bags, crow's feet, fine lines, freckles, sun spots, uneven skin tone, or dullness).

Willing to complete 3 study visits within 4 weeks, comply with instrumental measurements, and maintain product logs.

Willing to sign the Informed Consent Form (ICF).

Disqualifiers

Received facial aesthetic treatments (e.g., lasers, chemical peels, microneedling, energy-based therapies) within 4 weeks.

Used topical/oral retinoic acid or strong whitening creams (e.g., high-concentration hydroquinone) within 4 weeks.

Severe sensitive skin, active atopic dermatitis, or obvious facial skin lesions/infections.

Facial salon or exfoliation treatments more frequent than once every 2 weeks.

Trial design

Design model

Single group

Treatments tested in this trial

Deep Microspicule Cream
Other intervention
"A topical cream (Deep Microspicule Cream) utilizing patented crystal microspicule technology to encapsulate Penghu seaweed extracts (including Caulerpa microphysa, Sargassum hemiphyllum, and Botryocladia leptopoda). These ingredients possess potential anti-inflammatory, antioxidant, and collagen-promoting properties. Participants will apply a green-bean-sized amount of the cream strictly to the randomly assigned intervention side of the face (left or right). The cream should be massaged gently on the designated side to allow the microspicules to roll on the skin surface (avoiding harsh rubbing). This application regimen is to be performed three times per week (Mondays, Wednesdays, and Saturdays) at night after facial cleansing, for a total duration of 28 days."

Treatment groups

10 Participants

are divided into 1 treatment group

Group A: Split-Face Control GroupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

Skin Hydration,Transepidermal Water Loss (TEWL),Skin Elasticity,Erythema Index,Skin Color

"Using the Cutometer® MPA 580 to sequentially measure skin hydration, transepidermal water loss (TEWL), skin elasticity, erythema index, and skin color."

Time frame

Baseline (Day 0), Day 14, Day 28

Secondary outcomes

skin texture smoothness, visual radiance (glossiness), and skin firmness

"Subjective evaluation of skin improvement including skin feel (texture smoothness), visual radiance (glossiness), and skin firmness, assessed via a 7-point Likert scale (ranging from 1 = very dissatisfied to 7 = very satisfied) .

Time frame

Baseline (Day 0), Day 14, Day 28

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Chung Shan Medical University

Lead sponsor

Source ClinicalTrials.gov

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