Electroacupuncture Treatment of Peripheral Neuropathy After Taxane Chemotherapy for Breast Cancer

ConditionBreast Cancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-75
SponsorAffiliated Hospital of Qinghai University

About this trial

Electroacupuncture treatment of peripheral neuropathy after taxane chemotherapy for breast cancer

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Breast cancer patients diagnosed by pathology;

EOOG score is 0 or 1;

The age range for enrollment is between 18 and 75 years old; ④ Accept chemotherapy regimens based on taxane drugs (alone or in combination);

Accept regular follow-up visits; ⑨ There is complete pathological data available.

Disqualifiers

Non breast cancer patients;

Received electroacupuncture treatment within 6 months prior to the start of the study;

Patients who experience intolerable toxic side effects during standard dose chemotherapy and terminate the chemotherapy cycle;

Prior to enrollment, there was a history of peripheral neuropathy;

Trial design

Design model

Parallel

Treatments tested in this trial

  • Electro-acupuncture

    Behavioral

    A method of acupuncture that combines acupuncture with a certain frequency of electrical stimulation. Electrical stimulation is a mild level of stimulation intensity that is acceptable to the human body.

Treatment groups

162 Participants
are divided into 2 treatment groups
Group A: Electroacupuncture+Routine Nursing GroupExperimental treatment 1 intervention
Group B: Fake electroacupuncture + Routine Nursing GroupPlacebo comparator 1 intervention

Trial outcomes

Primary outcomes

1

Functional Assessment of Cancer Therapy/Gynecologic Oncology Group Neurotoxicity Index (FACT/GOG-NTX)

This scale is mainly used to evaluate chemotherapy induced peripheral neuropathy (CIPN), especially the neurotoxic reactions in gynecological tumor treatment. Through this scale, it is possible to quantify the neurotoxic symptoms that patients experience after receiving chemotherapy, such as sensory abnormalities, motor dysfunction, etc., in order to better monitor and manage the patient's health status.

Time frame
After enrollment, the first assessment of the scale will be conducted, followed by another assessment of the scale at the 4th and 8th week of treatment (7 days per week).

Secondary outcomes

1

The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire CIPN-20.

This scale is used to evaluate the impact of chemotherapy induced peripheral neuropathy (CIPN) on the quality of life of patients.

Time frame
After enrollment, the first assessment of the scale will be conducted, followed by another assessment of the scale at the 4th and 8th week of treatment (7 days per week).

Other outcomes

Sponsors and contacts

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