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Elicitation of Steady-state Audiovisual Responses in 6- and 10-month-old Infants

ConditionSpeech
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6-10
SponsorInstitut Pasteur

About this trial

The goal of this study is to investigate the preferential responses of speech neural systems in infants.

The main question it aims to answer is to determine whether the oscillatory synchronization capacity is associated with children's language level (i.e. vocabulary).

Participants will be presented with synthetically modulated stimuli at three frequency scales: 4 Hz, 5 Hz and 30 Hz.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

be 6 or 10 months old (+/- 2 weeks)

have received age-appropriate information on the experiment

their legal guardians have received appropriate information and given their oral consent.

Disqualifiers

A neurological disorder (visual, auditory, motor, executive)

Developmental delay

Trial design

Design model

Parallel

Treatments tested in this trial

  • Magnetoencephalography (MEG)

    Behavioral

    Stimuli will be presented binaurally through headphones at 60 decibel sound pressure level (dB SPL). Conditions are presented in a pseudo-random order with an inter-stimulus interval of \~800 ms on average (range: 600 ms to 1000 ms). The duration of the stimuli is fixed: 2 seconds, in order to guarantee a minimum number of cycles.

  • Cognition development questionnaire

    Other intervention

    Computerised questionnaires completed by parents

Treatment groups

64 Participants
are divided into 2 treatment groups
Group A: 6-month-old infantsOther 2 interventions
Group B: 10-month-old infantsOther 2 interventions

Trial outcomes

Primary outcomes

1

Significance of correlation between the delta (i.e. difference) of synchronization power estimated at 10- and 6-months of age and the delta of vocabulary level measured at 18months of age.

Time frame
at 10-months, 6-months and 18-months of age

Secondary outcomes

1

The equation for linear regression analysis used to estimate the amount of neuronal synchronization between auditory and visual perception systems according to the Coherence and the Synchrony of AV inputs

Time frame
at 10- and 6-months of age
2

The equation for linear regression analysis used to estimate the variation in the amount of neuronal synchronization between 4 experimental conditions according to the Coherence and the Synchrony of AV inputs

4 experimental conditions : AV synchronous coherent, AV asynchronous coherent, AV synchronous incoherent, and AV asynchronous incoherent

Time frame
at 10- and 6-months of age

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Institut Pasteur

Lead sponsor

Institut de l'Audition

Collaborator

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: