Elimination Diet Strategies and Histologic Remission in Children With Eosinophilic Gastrointestinal Disorders
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age2-18
SponsorCukurova University
About this trial
This prospective observational cohort study aims to evaluate clinical and histologic outcomes of elimination diets in children aged 2-17 years with eosinophilic gastrointestinal disorders (EGIDs). The type of elimination diet will be determined by the treating physician as part of routine clinical care according to each patient's clinical characteristics. The study will not assign participants to a specific dietary treatment. Clinical symptoms, histologic findings, growth parameters, and nutritional outcomes will be prospectively recorded. Follow-up endoscopy and biopsies performed as part of routine clinical care will be used to assess histologic response. Food reintroduction and disease recurrence will also be evaluated during follow-up.
Eligibility criteria
Qualifiers
Age 2-17 years.
Presence of gastrointestinal symptoms such as abdominal pain, vomiting, diarrhea, hematemesis, or hematochezia.
Undergoing upper and/or lower gastrointestinal endoscopy for a clinical indication.
Histologic eosinophilic infiltration consistent with an eosinophilic gastrointestinal disorder.
Disqualifiers
Inflammatory bowel disease, parasitic infection, celiac disease, drug-associated enteropathy, hypereosinophilic syndrome, or other identified causes of gastrointestinal eosinophilia.
Known primary immunodeficiency.
Active malignancy.
Systemic rheumatologic disease.
Trial design
Treatments tested in this trial
- Elimination Diet
Treatment groups
34 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov