EMDR Treatment of Conditioned Nausea and Vomiting in Cancer Survivors

ConditionCancer Survivors

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age16+

SponsorUniversity Medical Center Groningen

About this trial

To explore the effectiveness of EMDR therapy treatment in reducing symptoms of chemotherapy-induced conditioned nausea and vomiting in (former) patients with cancer.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Previously pathologically confirmed diagnosis of cancer

Previously treated with systemic cancer therapy

Persistent complaints (more than 2 months) of conditioned nausea and/or vomiting

Able to understand spoken and written Dutch

Disqualifiers

Ongoing psychiatric treatment

EMDR therapy contraindications (dissociative disorders, personality disorders or severe somatic disorders (e.g. cardiac arrhythmias))

Complex type 2 trauma

Known with recent conditions / non-anti-cancer medication which can elicit nausea (e.g. pregnancy or alcohol abuses)

Trial design

Design model

Single group

Treatments tested in this trial

EMDR therapy
Other intervention
In this study, EMDR therapy will be performed by psychologists of the UMCG who are trained in EMDR therapy and who have experience with patients with somatic diseases. In the EMDR therapy protocol, the patient is guided through eight phases which incorporate dual focus of attention and alternating bilateral visual, auditory, and/or tactile stimulation (see supplement for protocol). The number of sessions varies per patient (1-3 sessions), depending on the desensitization of the conditioned stimuli. The sessions will last 60-90 minutes.

Treatment groups

20 Participants

are divided into 1 treatment group

Group A: EMDR TherapyExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

Degree of conditioned nausea and vomiting

Degree of conditioned nausea and vomiting after exposure to conditioned stimuli using the nausea profile questionnaire measured using the nausea profile questionnaire (9-point Likert scale, higher scores = worse outcome)

Time frame

Before intake EMDR therapy session and three weeks after last EMDR therapy session

Secondary outcomes

Impact on QoL of conditioned nausea and vomiting

Impact on QoL of conditioned nausea and vomiting using Functional Living Index- Emesis (FLIE) questionnaire (7-point Likert scale, higher scores = better/worse outcome, depending on the question)

Time frame

Before EMDR therapy

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University Medical Center Groningen

Lead sponsor

Source ClinicalTrials.gov

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