A prospective, single-center, open-label, randomized controlled study to compare the effectiveness and safety of endoscopic mucosal resection (EMR) and cold snare polypectomy (CSP) in treating colorectal sessile serrated lesions (SSLs) less than 10mm in size.
Aged between 35 and 75 years
Suspected sessile serrated lesions less than 10mm in size in screening, surveillance or therapeutic colonoscopy
0-Is or 0-IIa according to Paris classification
Type 1 according to NICE and JNET classification
Unsuitable for removal by EMR or CSP
Suspected dysplasia or malignancy
Recurrent sessile serrated lesions after endoscopic resection
Familial adenomatous polyposis, Lynch syndrome or serrated polyposis syndrome