Endometrial Receptivity Prediction During in Vitro Fertilization Using Artificial Intelligence

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-40
SponsorGottsegen National Cardiovascular Institute

About this trial

The investigators plan to use artificial intelligence to analyse vaginal ultrasound images of the uterine lining (endometrium) taken during routine IVF treatment, which may predict implantation success during IVF treatment.

Participation in the study is voluntary, involves no additional testing or intervention beyond routine procedures, and consent can be withdrawn verbally or in writing at any time without cause or adverse consequences.

Over a three-year period, the trial is expected to enrol approximately 1,500 patients between the ages of 18 and 40 who are indicated for IVF treatment and who volunteer for treatment.

Patients enrolled in the study will not be required to attend more clinic visits during treatment than they would otherwise have to. During the trial, certain patient-specific data (age, indication for treatment, body mass index), stimulation-specific data (duration of stimulation, type and dose of drug, endometrial thickness), ultrasound scans and outcome-specific data (treatment failure, biochemical pregnancy, clinical pregnancy) will be collected. The data will be stored in a secure database. The data collected during the study will only be accessible to the professionals involved in the study and no information, including personal data, will be disclosed to third parties.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Female patient 18-40 years, for whom IVF is indicated

Maximum 3 unsuccessful previous embryo transfers

Only cycles in which single blastocyst is transferred

Disqualifiers

Congenital uterine anomalies, fibroids, adenomyosis, Asherman-syndrome or any other conditions resulting in malformation of the uterus

Presence of hydrosalpinx

Endometriosis

Planned freeze-all cycle

Trial population

Patients who volunteer for IVF treatment at participating infertility centres

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Clinical pregnancy

Clinical pregnancy: pregnancy can be confirmed through ultrasound visualization of the gestational sac or heartbeat

Time frame
The date of the ultrasound confirmed clinical pregnancy scheduled at 28 days following embryo transfer

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Gottsegen National Cardiovascular Institute

Lead sponsor

Dunamenti REK Reprodukcios Kozpont

Collaborator