About this trial
The study aims to retrospectively investigate the endoscopic resection procedures of cancerous and precancerous lesions of the upper and lower digestive tract in order to evaluate the efficacy and safety outcomes and to compare different resection techniques. In particular, the resection techniques investigated will be mucosectomy, en bloc and piecemeal, endoscopic submucosal dissection (ESD) and its variants, full-thickness resection. The anatomical districts involved will be the esophagus, stomach, duodenum, colon and rectum.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
18 years or older
all patients who have undergone endoscopic resection of an upper or lower digestive tract tumor
Disqualifiers
age under 18
inability to provide informed consent
Trial population
Patients\> 18 years of age who have undergone endoscopic resection of cancerous or pre-cancerous lesions of the digestive tract will be included in the study
Trial design
Cohort
Retrospective
Treatments tested in this trial
Endoscopic resection
Procedure/SurgeryThe endoscopic resection is the procedure that allows to remove cancerous or precancerous conditions of digestive tract. Endoscopic resection can be preformed by several techniques: 1. Endoscopic mucosal resection (EMR): it allows to remove mucosal lesions 2. Endoscopic submucosal dissection: it allows to remove mucosal lesions that involved submucosal layer and large lesions 3. Full-thickness resection: it allows to remove infiltrating lesions by the resection of a little piece of the entire gastrointestinal wall
Treatment groups
Trial outcomes
Primary outcomes
en bloc resection rate
the en bloc resection is the ability to remove the neoplasia in a single piece
complete resection rate
the complete resection is the ability to remove the neoplasia with clear margins (R0)
recurrence rate
recurrence is the recurrence of the neoplasm at the resection site during follow-up
Secondary outcomes
adverse events rate
complication rate, early or late, related to the procedure used for endoscopic resection
costs
evaluation of the costs incurred to perform the endoscopic resection
Sponsors and contacts
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