Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia

ConditionsHypoxia Airway Obstruction, Postoperative Sore Throat Cough, Postoperative

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18+

SponsorMahidol University

About this trial

The goal of this study is to determine whether omitting tracheal suctioning immediately prior to extubation is non-inferior to routine tracheal suctioning with respect to early postoperative oxygenation among adult surgical patients (aged 18-90 years, American Society of Anesthesiologists \[ASA\] physical status I-III) undergoing elective surgery under general anesthesia with endotracheal intubation.

The study addresses the following questions:

* Primary outcome (non-inferiority): * Is the risk of postoperative desaturation (oxygen saturation \[SpO₂\] \<92% within 60 minutes after extubation) in the no-suction group not worse than in the routine-suction group by more than 10 percentage points? * Secondary outcomes (superiority): * Does omitting tracheal suctioning reduce postoperative cough severity and sore throat? * Does omitting tracheal suctioning avoid increasing extubation-related adverse events?

Participants will be randomly assigned (1:1) to one of two groups:

* Routine suctioning (SUC): Endotracheal suctioning plus oropharyngeal suctioning immediately before extubation * No suctioning (NON-SUC): Oropharyngeal suctioning only, without endotracheal suctioning

All participants will receive standard anesthetic care and postoperative monitoring in the post-anesthesia care unit (PACU) for 60 minutes. Follow-up for airway symptoms and patient satisfaction will be conducted at 24 hours after surgery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults aged 18-90 years with American Society of Anesthesiologists (ASA) physical status I-III.

Scheduled for elective surgery under general anesthesia requiring endotracheal intubation.

Planned tracheal extubation in the operating room at the end of surgery.

Disqualifiers

Inability to provide informed consent or the presence of a significant language barrier that prevents effective communication with the clinical team.

Known diagnosis of obstructive sleep apnea (OSA), active pneumonia, or chronic pulmonary disease (e.g., chronic obstructive pulmonary disease, restrictive lung disease).

Body mass index (BMI) >35 kg/m².

Pregnancy or increased aspiration risk (e.g., full stomach).

Trial design

Design model

Parallel

Treatments tested in this trial

Routine Endotracheal Suctioning
Procedure/Surgery
Endotracheal suctioning performed immediately prior to extubation using standard suction pressure and technique. Oropharyngeal suctioning was also performed according to routine clinical practice.
Omission of Endotracheal Suctioning
Procedure/Surgery
Oropharyngeal suctioning only was performed prior to extubation. No suction catheter was inserted into the trachea.

Treatment groups

408 Participants

are divided into 2 treatment groups

Group A: Routine Endotracheal Suctioning (SUC)Active comparator 1 intervention

Group B: Omission of Endotracheal Suctioning (NON-SUC)Experimental treatment 1 intervention

Trial outcomes

Primary outcomes

Incidence of postoperative desaturation after extubation

Proportion of participants who develop desaturation, defined as peripheral oxygen saturation (SpO₂) \<92% at any time within the first 60 minutes after extubation.

Time frame