Energy CT in Imaging and Diagnosis of Gastric Cancer
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorThe First Affiliated Hospital of Zhengzhou University
About this trial
Accurate preoperative prediction of risk stratification, treatment response, and survival prognosis in gastric cancer is important for improving clinical treatment decisions, prolonging patient survival, and improving patient quality of life. The purpose of this study is to investigate the performance of the multi-parametric magnetic resonance imaging (mpMRI) and Dual-/Muti-energy CT and photon-counting Detector CT(PCD-CT) in the diagnosis and management of gastric cancer.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Pathological biopsy confirmed gastric cancer;
Surgery: patients undergoing radical gastrectomy. Patients undergoing exploratory abdominal surgery or palliative tumor resection were still included in the study when peritoneal metastasis or adjacent organ invasion was identified intraoperatively and radical surgical resection was not possible.
Disqualifiers
Refusal or inability to sign informed consent;
CT or MRI images are poor or the focus is small and CT images are not clear;
Patients with other tumors complicated with patients with important organ dysfunction.
Trial population
For patients undergoing radical resection, abdominal exploration or palliative tumor resection, CT scanning and dynamic contrast-enhanced magnetic resonance DCE-MRI scanning shall be completed in GSI mode before operation; for patients undergoing neoadjuvant chemotherapy, CT scanning and dynamic contrast-enhanced magnetic resonance DCE-MRI scanning shall be completed in GSI mode before neoadjuvant chemotherapy at least, and if the above scanning mode can still be used during chemotherapy, it is the best choice. Signed informed consent form. Patients who were diagnosed with gastric cancer at various medical centers were included in this study
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
computerized tomography
DevicempMRI and Photon-counting Detector CT scan
Treatment groups
300 Participants
are divided into 1 treatment groupGroup A: GC group1 intervention
Trial outcomes
Primary outcomes
1
Diagnostic and Predictive performance of Dual-/ Muti- energy CT and MRI in the treatment response and survival prognosis of gastric cancer
Accuracy for both imaging techniques in the prediction of treatment response of gastric cancer.
Time frame
3yearsSecondary outcomes
1
The kappa value; One-way analysis of variance; ICC
Consistency of the Photon-counting Detector CT and mpMRI in tumor assessment
Time frame
1yearSponsors and contacts
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Source ClinicalTrials.gov