About this trial
This clinical trial studies engagement strategies for recruiting American Indians (AI) of Southwestern Tribal Nations for cancer genome sequencing. American Indians in the Southwest have higher rates of some types of cancer, such as cancers that arise in the liver, kidney, breast, and colon. American Indians with cancer may also live for less time than people from other population groups who have been treated for the same cancer. Damage to the cells of the body, acquired as people live, grow older, and are exposed to the environment, causes genetic changes in cells that can lead to cancer. This study may help researchers learn how these genetic changes in cells cause cancer and understand how and why cancer is arising in American Indians in the Southwest. This may help better prevent and treat cancer in the future.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
The PE-CGS Research Center is only recruiting and sequencing tumors for adult-onset cancers (patients and survivors) among the American Indian Tribes, Nations, and Pueblos of New Mexico and adjacent states
Male or female adults (18 years) or older
Cancer patient undergoing active treatment or a cancer survivor
Self-identify as American Indian
Disqualifiers
Cognitively impaired
Adults unable to consent for themselves
Individuals who are not yet adults
Prisoners
Trial design
Sequential
Treatments tested in this trial
Biospecimen Collection
Procedure/SurgeryUndergo collection of tissue, blood, saliva, and stool samples
Return of Results
Procedure/SurgeryReceive results
Survey Administration
Other interventionSurveys and Interviews
Treatment groups
Trial outcomes
Primary outcomes
Total Enrolled Participants
Number and percent of eligible participants enrolled and consented
Data participation rate
Number and percent of eligible participants who complete, or partially complete, baseline and follow up data collection of epidemiological assessments and follow up data collection of epidemiological assessments
Biospecimen participation rate
Number and percent of enrolled participants for whom biospecimens are collected and processed for genomic analysis
Rate of comprehensive genomic analysis completion
Number and percent of participants/samples that undergo successful comprehensive genomic and bioinformatic analysis
Sponsors and contacts
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New Mexico Cancer Research Alliance
Lead sponsor
National Cancer Institute (NCI)
Collaborator