Engagement of American Indians of Southwestern Tribal Nations in Cancer Genome Sequencing

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorNew Mexico Cancer Research Alliance

About this trial

This clinical trial studies engagement strategies for recruiting American Indians (AI) of Southwestern Tribal Nations for cancer genome sequencing. American Indians in the Southwest have higher rates of some types of cancer, such as cancers that arise in the liver, kidney, breast, and colon. American Indians with cancer may also live for less time than people from other population groups who have been treated for the same cancer. Damage to the cells of the body, acquired as people live, grow older, and are exposed to the environment, causes genetic changes in cells that can lead to cancer. This study may help researchers learn how these genetic changes in cells cause cancer and understand how and why cancer is arising in American Indians in the Southwest. This may help better prevent and treat cancer in the future.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

The PE-CGS Research Center is only recruiting and sequencing tumors for adult-onset cancers (patients and survivors) among the American Indian Tribes, Nations, and Pueblos of New Mexico and adjacent states

Male or female adults (18 years) or older

Cancer patient undergoing active treatment or a cancer survivor

Self-identify as American Indian

Disqualifiers

Cognitively impaired

Adults unable to consent for themselves

Individuals who are not yet adults

Prisoners

Trial design

Design model

Sequential

Treatments tested in this trial

  • Biospecimen Collection

    Procedure/Surgery

    Undergo collection of tissue, blood, saliva, and stool samples

  • Return of Results

    Procedure/Surgery

    Receive results

  • Survey Administration

    Other intervention

    Surveys and Interviews

Treatment groups

1,001 Participants
are divided into 1 treatment group
Group A: Category 1 (biospecimens, surveys, interviews)Experimental treatment 3 interventions

Trial outcomes

Primary outcomes

1

Total Enrolled Participants

Number and percent of eligible participants enrolled and consented

Time frame
Up to 18 months
2

Data participation rate

Number and percent of eligible participants who complete, or partially complete, baseline and follow up data collection of epidemiological assessments and follow up data collection of epidemiological assessments

Time frame
Up to 18 months
3

Biospecimen participation rate

Number and percent of enrolled participants for whom biospecimens are collected and processed for genomic analysis

Time frame
Up to 18 months
4

Rate of comprehensive genomic analysis completion

Number and percent of participants/samples that undergo successful comprehensive genomic and bioinformatic analysis

Time frame
Up to 18 months

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

New Mexico Cancer Research Alliance

Lead sponsor

National Cancer Institute (NCI)

Collaborator