Enhanced Community First Responder System Evaluation in Singapore

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21+
SponsorSingapore General Hospital

About this trial

The rise in out-of-hospital cardiac arrest (OHCA) cases in Singapore highlights the need for effective bystander cardiopulmonary resuscitation (BCPR). Despite many lay responders performing CPR, survival rates with good neurological outcomes have not significantly improved, prompting research into the quality of CPR as a critical factor. The study by Gallagher EJ et al. showed a significant survival improvement with high-quality CPR.

To address this, the Unit of Pre-hospital and Emergency Research (UPEC) trained thousands of community first responders (CFRs) in simplified CPR techniques using hands-only and DA-CPR methods. A significant innovation is the CPRcard®, developed by Laerdal in Norway, which offers real-time feedback on the quality of chest compressions. However, only 36% of CFRs using the CPRcard® achieved the desired compression standards, indicating room for improvement.

The study proposes enhancing CFR support with information communication technology (ICT), enabling two-way audio and one-way video communication between CFRs and dispatchers. This aims to reduce stress among responders, increase their willingness to engage with OHCA alerts, and improve CPR quality.

The clinical trial in Singapore will compare the current system against the enhanced CFR support system (eCSS), focusing on the real-time relay of CPR performance data, communication ease, and implementation factors. The high-quality CFR and OHCA registries in Singapore provide a robust setting for this research, aiming to enhance CPR delivery and improve OHCA outcomes through technology and real-time support.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

18 years old and above

SCDF registered CFRs

Trial dispatchers with an active account of myResponder® app on their mobile phones

Disqualifiers

The CFRs who are pregnant

Experiencing any serious physical Conditions

Mental Health Conditions

Trial design

Design model

Parallel

Treatments tested in this trial

  • CPRCard + TCPR Link App and Web

    Device

    Application that allows responder to perform CPR with two-way audio communication and one-way video streaming to SCDF Dispatcher

  • CPRCard Only

    Device

    Control arm with standard care of procedure that Bystander using CPRCard only

Treatment groups

165 Participants
are divided into 2 treatment groups
Group A: SoCActive comparator 1 intervention
Group B: eCSSExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Good Chest Compression Depth (4-6cm)

OHCA events achieving great proportions of adequate compressions (achieving depth within the target range of 4-6 cm)

Time frame
Throughout chest compression before handing over to EMS (up to 24 hours)

Secondary outcomes

1

Survivor discharging rate

Return of spontaneous circulation (ROSC) at scene or at emergency department; survival to discharge; neurologically intact survival

Time frame
Throughout Hospital Admission (up to 1 year)

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Singapore General Hospital

Lead sponsor

Duke-NUS Graduate Medical School

Collaborator