Enhanced COPD Management in Suspected Lung Cancer Patients

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorDitte Krag-Hansen

About this trial

Identifying and treating COPD in patients undergoing lung cancer evaluation is crucial. Early intervention could lead to better management of both diseases, improving health status, reducing healthcare costs, and potentially increasing survival rates.

This study aims to assess the impact of early diagnosis and optimal treatment of COPD on clinical outcomes in patients under evaluation for lung cancer. The study will combine information through an open-label RCT at the Lung Cancer Investigation Unit at Lillebaelt Hospital Vejle.

The findings could inform clinical practice by emphasizing the importance of integrated care approaches for patients with coexisting COPD and lung cancer, ultimately leading to better health outcomes.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Undergoing diagnostic evaluation for suspected lung cancer

Spirometry showing obstructive airflow limitation (FEV₁/FVC < 75 % or FEV₁ < 80 %, and no reversibility) at the first outpatient visit at the lung cancer evaluation

Disqualifiers

Presence of significant comorbidities that may interfere with diagnostic procedures or spirometry

Pregnant or breastfeeding women

Trial design

Design model

Parallel

Treatments tested in this trial

  • Tailored COPD consultations

    Other intervention

    These consultations will include assessment and treatment according to GOLD guidelines, including: Pharmacological management Smoking cessation support Referral to pulmonary rehabilitation as appropriate Referral for nutritional assessment and optimization when appropriate Referral to cardiovascular evaluation when appropriate Referral to sleep apnea evaluation when appropriate

Treatment groups

280 Participants
are divided into 2 treatment groups
Group A: Usual careNo intervention 0 interventions
Group B: Tailored COPD consultationExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

CAT score

CAT consists of a questionnaire with eight items with the possibility of scoring 0-40 on respiratory symptoms. Participants will be tested at baseline, and after a follow-up period of 3 and 6 months after enrollment of the study.

Time frame
Baseline, after 3 months and after 6 months

Secondary outcomes

1

Weight

kg Reviews the change

Time frame
Baseline and after 6 months
2

Height

cm

Time frame
Basline
3

BMI

kg/m\^2 Reviews the change

Time frame
Baseline and after 6 months
4

1 min sit-to-stand-test

The higher the number the better

Time frame
Baseline and after 6 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Ditte Krag-Hansen

Lead sponsor

Region of Southern Denmark

Sponsor institution

AstraZeneca

Collaborator

Sygehus Lillebaelt

Collaborator