About this trial
Several psychotherapies for posttraumatic stress disorder (PTSD) have a strong evidence base for their efficacy, but nonresponse rates are high, particularly among older Veterans. Accumulating evidence indicates that memory deficits and poor learning of therapy contents adversely affect psychotherapy treatment response in PTSD. However, limited research has examined methods for increasing learning of therapy contents in psychotherapy for PTSD. The proposed study aims to examine the feasibility of integrating an intervention to increase learning and memory of psychotherapy content into the provision of a widely used psychotherapy, cognitive processing therapy (CPT), for older adults with PTSD. The ultimate goal of this line of research is to develop novel rehabilitation interventions to increase functioning for individuals with PTSD.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Veterans with DSM-5 diagnoses of PTSD via the Clinician Administered PTSD Scale (CAPS-5)
Disqualifiers
daily benzodiazepine use (due to memory impairing effects)
bipolar or psychotic disorders
current suicidal ideation with plan or intent
current moderate or severe substance use disorder not in remission for >1 month
Trial design
Single group
Treatments tested in this trial
Cognitive Processing Therapy
BehavioralCPT as described in the treatment manual
Cognitive Processing Therapy (CPT) + Memory Support
BehavioralCPT+Memory support will also incorporate frequent and intentional use of strategies to enhance learning and memory of this content.
Treatment groups
Trial outcomes
Primary outcomes
PTSD Checklist-5 (PCL-5)
Questionnaire for symptoms of PTSD; the range of the scale is from 0 (no symptoms) to 80 (maximal symptoms)
Other outcomes
Client Satisfaction Questionnaire (CSQ)
8-item patient satisfaction scale; the range of the scale is from 8 to 32, where low scores are indicative of low satisfaction and high scores are indicative of high satisfaction
Sponsors and contacts
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