The goal of this clinical trial is to learn whether the Lexical Association Technique (LAT) can improve well-being in people recently diagnosed with multiple sclerosis (MS), either relapsing-remitting (RRMS) or secondary progressive (SPMS).
The main questions it aims to answer are:
* Does the LAT increase well-being more than a placebo technique ? * Does this technique help reduce psychological distress and improve quality of life ?
Participants will:
* Be randomly assigned to either the LAT group or the active control group * Complete short visualization exercises at home using a personal computer * Fill out questionnaires about self-esteem, stress, anxiety, depression, quality of life, and adjustment to illness * Take part in the study over several weeks, with assessments before, after, and 14 days after the intervention
Researchers will compare results between the two groups (LAT group vs. Control group) to test the immediate and lasting effects of the LAT.
Native French speaker
Access to a computer and internet connection at home
Diagnosis of multiple sclerosis according to the revised criteria of Thompson et al. (2018), either relapsing-remitting or secondary progressive form, between 1 and 5 years since disease onset (RRMS or SPMS entry phase)
Currently receiving first- or second-line oral treatment (e.g., Teriflunomide, Dimethylfumarate, Fingolimod, Cladribine)
Participants not presenting with low self-esteem, i.e., score >26 on the Self-Esteem Scale (EES; Vallières & Vallerand, 1990)
Major life event significantly affecting well-being in the two weeks prior to study inclusion (e.g., bereavement, separation, childbirth, etc.)
Initiation of psychological, psychiatric, or pharmacological treatment (anxiolytics, antidepressants) within one month prior to study start
University Hospital, Grenoble
Lead sponsor
Laboratoire interuniversitaire de psychologie : personnalité, cognition et changement social - LIP-PC2S
Collaborator
Laboratoire de Psychologie et NeuroCognition
Collaborator