Enucleation of Pancreatic Tumor by Blocking Abdominal Trunk and Superior Mesenteric Artery
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age14-70
SponsorZhejiang University
About this trial
Pancreatic enucleation could preserve more healthy pancreatic tissues and functions with a low recurrence risk. However, conventional enucleation can cause significant intraoperative bleeding, especially in which tumors in the pancreatic head, neck, and uncinate process of pancreas, as these tissues are rich in blood supply, mainly including the abdominal trunk and the superior mesenteric artery. In this study, we developed a novel method to control the pancreatic blood flow in laparoscopic enucleation--blocking the abdominal trunk and superior mesenteric artery with vascular occlusion clips in the process of resection, and evaluated its effectiveness and safety.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Benign or borderline tumors diagnosed pathologically, such as pancreatic neuroendocrine tumors, solid pseudopapillary tumors, and cystadenomas, without vascular invasion or distant metastasis
Tumors sited in the pancreatic head, neck, and uncinate process of pancreas
Blockade of both the abdominal trunk and superior mesenteric artery in the laparoscopic enucleation
Disqualifiers
Highly malignant pancreatic tumors, or tumors with infiltration or metastasis
Tumors of the body and tail of the pancreas
Transfer to LPD or laparotomy
Trial design
Design model
Single group
Treatments tested in this trial
blocking both the abdominal trunk and superior mesenteric artery in the pancreatic enucleation
Procedure/SurgeryIn the pancreatic enucleation, Kocher Maneuver was routinely performed at first. Then free the left side of the abdominal trunk and superior mesenteric artery, loose tissues easy to free.After Kocher Maneuver and other surgical procedures, the abdominal trunk and superior mesenteric artery exposed. Before resection of pancreatic tumors, a vascular occlusion clamp clip was used to block the root of both the abdominal trunk and superior mesenteric artery to control the pancreatic blood flow.
Treatment groups
30 Participants
are divided into 1 treatment groupGroup A: blockade of arteries in laparoscopic pancreatic enucleationExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
blood loss
blockade of both the abdominal trunk and superior mesenteric artery changes the blood loss
Time frame
in the procedureSponsors and contacts
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Source ClinicalTrials.gov