Eosinophilic Esophagitis: Towards Improved Management
ConditionEosinophilic Esophagitis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 17
SponsorOslo University Hospital
About this trial
The current project aims to improve the care for children and adolescents with eosinophilic esophagitis in a collaborative effort involving pediatric units at Oslo Unversity Hospital and Helse Bergen, Norway. Existing and new non-invasive biomarkers will be explored systematically, aiming to reduce the number of endoscopies and time on restricted diet.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
a diagnosis of eosinophilic esophagitis
suspected but not yet confirmed eosinophilic esophagitis
Disqualifiers
chronic severe conditions that preclude general anaestesia
lack of consent
Trial population
Children with newly diagnosed or previously confirmed eosinophilic esophagitis.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Biobank sampling for new biomarkers
Other interventionUsing biopsies as the gold standard, the project aims towards validating non-invasive biomarkers as specified previously against biopsies.
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
Active eosinophilic esophagitis (>15 eosinophils per high-power field)
The eosinophil counts in a biopsy is used to classify active vs non-active eosinophilic esophagitis, and biomarkers are analysed using biopsy the gold standard to classify active vs inactive disease.
Time frame
12 monthsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Oslo University Hospital
Lead sponsor
Helse-Bergen HF
Collaborator
Source ClinicalTrials.gov