Epicardial Fat Tissue and Cardiometabolic Risk in Russian and Asian Populations

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age50-70
SponsorNational Medical Research Center for Therapy and Preventive Medicine

About this trial

Visceral obesity is a well-established risk factor for the development of chronic non-communicable diseases (NCDs). Epicardial fat tissue (EFT) is located on the surface of the myocardium and may directly affect cardiac function and contribute to structural and functional remodeling.

According to the literature, increased EFT thickness is associated with a wide range of NCDs, disease severity, and prognosis.

The aim of this study is to investigate the associations between EFT thickness and clinical and anamnestic parameters, as well as to evaluate the prognostic value of this parameter in patients aged 50-70 years from the Russian Federation, Kazakhstan, Uzbekistan, and Kyrgyzstan.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients aged 50-70 years undergoing transthoracic echocardiography in inpatient or outpatient settings;

Ability and willingness to provide informed consent.

Disqualifiers

Refusal to sign informed consent;

Inability to perform transthoracic echocardiography or poor image quality;

Severe psychiatric disorders.

Trial population

Patients from the Russian Federation, Kazakhstan, Uzbekistan, and Kyrgyzstan

Trial design

Design model

Cohort

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

500 Participants
are grouped into 1 trial group
Group A: Observational cohort

Trial outcomes

Primary outcomes

1

Composite endpoint - all-cause mortality - hospitalizations - major adverse cardiovascular events (MACE)

Time frame
12 months

Secondary outcomes

Other outcomes

Sponsors and contacts

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