About this trial
Retrospective, multicenter, non-profit observational study. The study will include consecutive patients who underwent lower-limb megaprosthesis implantation at the participating Centers between January 1, 2020, and June 30, 2023.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age ≥ 14 years
Implantation of a lower-limb megaprosthesis at one of the participating centers between January 1, 2020, and June 30, 2023
At least 2 years of follow-up after megaprosthesis implantation
Signed informed consent
Disqualifiers
None
Trial population
All patients aged 14 years or older who underwent implantation of a lower-limb megaprosthesis at the participating Centers between January 1, 2020, and June 30, 2023, will be included.
Trial design
Cohort
Retrospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Percent of patients with and without a diagnosis of megaprosthesis infection
Distribution of the study variables in the two groups of patients with and without megaprosthesis infection
Secondary outcomes
Number of patients diagnosed with lower-limb megaprosthesis infection / number of patients who received a lower-limb megaprosthesis
Sex, Charlson index, indication for prosthesis placement, symptoms and etiology of the infection in patients diagnosed with megaprosthesis infection
Age of patients diagnosed with megaprosthesis infection
Number and type of surgical procedures performed for the treatment of megaprosthesis infection
Sponsors and contacts
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