Epigenetic and Cortisol Level Reflections of Maternal Stress During Pregnancy
ConditionPregnancy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-49
SponsorKahramanmaras Sutcu Imam University
About this trial
The aim of this study is to evaluate the effects of stress management and epigenetic awareness training provided in prenatal classes on maternal stress levels, cortisol levels, and epigenetic awareness.
The main questions it aims to answer are:
1. Do stress management and epigenetic awareness training provided in prenatal classes affect pregnant women's cortisol levels? 2. Does the training affect pregnant women's knowledge and awareness of epigenetic effects?
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Pregnant women aged 18 and older
Pregnant women in any trimester of pregnancy
Pregnant women who can read and understand Turkish
Pregnant women who voluntarily agree to participate in the study
Disqualifiers
Foreign nationals with communication difficulties,
Multiple pregnancies,
Illiterate pregnant women,
Migrant pregnant women who do not speak Turkish,
Trial design
Design model
Crossover
Treatments tested in this trial
Maternal Epigenetics Training Module
BehavioralThe Maternal Epigenetics Education Module is a structured educational intervention designed to reduce stress levels in expectant mothers during pregnancy, raise their awareness of the effects of stress on both the mother and the fetus, and promote healthy lifestyle behaviors within the framework of epigenetic mechanisms. The module addresses the relationship between stress, epigenetics, and fetal health during pregnancy from a scientific perspective and aims to equip expectant mothers with basic skills for managing stress.
Treatment groups
140 Participants
are divided into 2 treatment groupsGroup A: Education groupExperimental treatment 1 intervention
Group B: ControlNo intervention 0 interventions
Trial outcomes
Primary outcomes
1
Assessment of Pregnancy-Related Stress
The Pregnancy Stress Assessment Scale , used to identify pregnancy-related stress factors in pregnant women. The scale consists of 36 items and 5 subscales. Range from a minimum of 0 to a maximum of 144 points. Higher scores on the scale are interpreted as indicating increased stress.
Time frame
Pregnancy Stress Assessment Scale will be administered to all pregnant women in both groups at the first interview (day 1)2
Assessment of Pregnancy-Related Stress
The Pregnancy Stress Assessment Scale , used to identify pregnancy-related stress factors in pregnant women. The scale consists of 36 items and 5 subscales. Range from a minimum of 0 to a maximum of 144 points. Higher scores on the scale are interpreted as indicating increased stress.
Time frame
Pregnancy Stress Assessment Scale will be administered to all pregnant women in both groups at the first interview (At the end of Week 3)Secondary outcomes
1
Measuring pregnant women's awareness of epigenetic effects and stress
This is a short questionnaire developed by the researcher to measure pregnant women's awareness of epigenetic effects and stress. It was designed to determine the level of awareness regarding the impact of stress during pregnancy on the baby's genetic and epigenetic structure, the importance of lifestyle changes, and the education provided, and was prepared by the researcher to assess the effect of maternal stress on epigenetic awareness. This form is designed to measure pregnant women's awareness of the effects of stress during pregnancy on the baby's genetic and epigenetic structure, the importance of lifestyle changes, and the level of awareness regarding the education provided at the Prenatal Education Program (Nowak et al., 2020). It will be evaluated based on the pregnant women's experiences and knowledge over the past month.
Time frame
Epigenetic Awareness and Information Form will be administered to all pregnant women in both groups at the first interview (day 1)2
Measuring pregnant women's awareness of epigenetic effects and stress
This is a short questionnaire developed by the researcher to measure pregnant women's awareness of epigenetic effects and stress. It was designed to determine the level of awareness regarding the impact of stress during pregnancy on the baby's genetic and epigenetic structure, the importance of lifestyle changes, and the education provided, and was prepared by the researcher to assess the effect of maternal stress on epigenetic awareness. This form is designed to measure pregnant women's awareness of the effects of stress during pregnancy on the baby's genetic and epigenetic structure, the importance of lifestyle changes, and the level of awareness regarding the education provided at the Prenatal Education Program (Nowak et al., 2020). It will be evaluated based on the pregnant women's experiences and knowledge over the past month.
Time frame
Epigenetic Awareness and Information Form will be administered to all pregnant women in both groups at the first interview (At the end of Week 3)3
Cortisol level measurement
Cortisol levels will be measured using saliva samples from pregnant women. Cortisol samples will be collected on an empty stomach between 8:00 and 9:00 a.m., and two samples will be collected from each participant-one before the training and one after the training.
Time frame
Salivary cortisol level will be administered to all pregnant women in both groups at the first interview (day 1)4
Cortisol level measurement
Cortisol levels will be measured using saliva samples from pregnant women. Cortisol samples will be collected on an empty stomach between 8:00 and 9:00 a.m., and two samples will be collected from each participant-one before the training and one after the training.
Time frame
Salivary cortisol level will be administered to all pregnant women in both groups at the first interview (At the end of Week 3)Sponsors and contacts
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Source ClinicalTrials.gov