ERAS in Choledochal Cyst & Biliary Atresia

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age1-14
SponsorMuhammad Zubair Shoukat

About this trial

This study aims to compare two feeding approaches after surgery for biliary atresia and choledochal cyst in children.

Traditionally, children are kept without oral feeding for more than 48 hours after these operations until bowel activity returns. However, newer Enhanced Recovery After Surgery (ERAS) programs suggest that starting feeding earlier may help children recover faster.

In this study, children undergoing surgery for biliary atresia or choledochal cyst will be randomly assigned to one of two groups. One group will start oral liquids within 24 hours after surgery and gradually progress to normal feeding as tolerated (early feeding group). The other group will receive conventional care, where feeding is started after more than 48 hours once bowel activity has returned.

Researchers will compare both groups for postoperative complications such as wound infection and anastomotic leakage, as well as the duration of hospital stay. Additional observations will include vomiting, abdominal distension, need for reinsertion of a nasogastric tube, requirement for repeat surgery, and time taken to resume normal feeding.

Participation in the study will not affect the standard surgical treatment provided. All children will receive routine perioperative care and will be monitored closely throughout their hospital stay and follow-up visits. The findings of this study may help determine whether early oral feeding is a safe and effective strategy to improve recovery and reduce hospitalization after pediatric hepatobiliary surgery.

Eligibility criteria

Qualifiers

All children diagnosed with choledochal cyst type I and IV on MRCP or CT scan, undergoing elective Roux-En-Y hepaticojejunostomy

All children with provisional diagnosis of biliary atresia undergoing Roux-En-Y portoenterostomy

Disqualifiers

Patients with suspected biliary atresia not undergoing portoenterostomy after Per-op cholangiogram either due to ruling out of disease or advanced disease deemed candidates for liver transplant

patients with history of Emergency surgery or external drainage of choledochal cyst

Hemodynamically unstable patients after surgery

Previous history of GI surgery

Trial design

Treatments tested in this trial

  • Enhanced Recovery After Surgery
  • Post-operative care

Treatment groups

100 Participants
are divided into 4 treatment groups

Sponsors and collaborators

Muhammad Zubair Shoukat

Lead sponsor

University of Child Health Sciences and Children's Hospital, Lahore

Sponsor institution

University of Child Health Sciences and Children's Hospital, Lahore

Collaborator