Erector Spina Plane Block Versus Modified Thoracoabdominal Nerve Block After Laparoscopic Cholecystectomy

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age30-65
SponsorAlexandria University

About this trial

direct comparisons between ESPB and M-TAPA for postoperative analgesia after LC remain limited. This is an important area of clinical interest because the two blocks differ significantly in their anatomical targets, mechanism of analgesia, and likely dermatomal coverage. The ESPB provides analgesia through paravertebral spread affecting both dorsal and ventral rami, thereby offering posterior and visceral pain relief, whereas M-TAPA directly targets the thoracoabdominal nerves, resulting in better anterior and lateral abdominal wall analgesia. Understanding which technique offers superior or more balanced analgesia could help to optimise regional anaesthesia strategies in LC and to improve patient outcomes.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age: between 30 - 65

American Society of Anaesthesiologists physical status: I- III

Body mass index: 18-35 kg.m-2

Disqualifiers

Patient Refusal

Allergy to local anaesthetic agents.

Skin infection at the site of injection.

Coagulopathy.

Trial design

Design model

Parallel

Treatments tested in this trial

  • bilateral ESP block

    Other intervention

    bilateral ESP block with injection of 20 ml 0.25% bupivacaine.

  • bilateral M-TAPA block

    Other intervention

    bilateral M-TAPA block with injection of 20 ml of 0.25% bupivacaine.

Treatment groups

50 Participants
are divided into 2 treatment groups
Group A: group 1Active comparator 1 intervention
Group B: group 2Experimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Time to First Analgesic request

minutes

Time frame
postoperative day 1

Secondary outcomes

1

Total Nalbuphine consumption

mg

Time frame
postoperative day 1
2

Visual analogue score

0 no pain , 10 severe pain

Time frame
postoperative day1
3

Quality of postoperative recovery

QOR 15

Time frame
postoperative day 1
4

Incidence of complications or adverse events

local anesthetic toxicity, bleeding

Time frame
postoperative day 5

Other outcomes

Sponsors and contacts

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