Health TrialsbyHealthPanel

ESP Versus PIFB for Analgesia in Open Cardiac Surgery: a Randomized Control Trial

ConditionAnalgesia
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorTaichung Veterans General Hospital

About this trial

This clinical trial compares analgesia efficiency and recovery outcomes between two different fascial plane block techniques (ESPB vs.PIFB) in cardiac surgery patients participant population/health conditions\].

The main questions it aims to answer are:

* Does ESPB provide superior analgesia than PIFB * Do patients who receive ESPB have better recovery outcomes

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults patients, elective and first-time cardiac surgery patients undergoing traditional sternotomy. Procedures include coronary artery bypass surgery, valve repair or replacement surgery, atrial and ventricular septal defect repair surgery, and other open-heart surgeries.

Disqualifiers

1. Emergency surgery 2. Anticipated combined major aortic vascular surgery 3. Already admitted to the ICU or on a ventilator before surgery.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Erector spinae plane block (ESPB)

    Procedure/Surgery

    Bilateral ESP: 0.5% ropivacaine 0.3 ml per kg (ideal body weight) each side, 30 min before skin excision. After surgery, use pump to deliver an intermittent automatic bolus of 0.3 ml per kg 0.16% ropivacaine every 4 hours each side.

  • Pecto-intercostal fascial plane blok (PIFB)

    Procedure/Surgery

    Bilateral PIFB: 0.5% ropivacaine 0.3 ml per kg (ideal body weight) each side, 30 min before skin excision. After surgery, use pump to deliver an intermittent automatic bolus of 0.3 ml per kg 0.16% ropivacaine every 4 hours each side.

Treatment groups

80 Participants
are divided into 2 treatment groups
Group A: Group EExperimental treatment 1 intervention
Group B: Group PActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

48hr opioid consumption

The primary outcome of this study was the total oral morphine equivalent (OME) dose received within 48 hours after surgery. OME was calculated using a conversion toolkit within our hospital's electronic medical record system, which standardizes opioid analgesic doses to oral morphine equivalents according to established guidelines

Time frame
Day 2

Secondary outcomes

1

Postoperative static pain scores-Day 1

Pain score reported by patients when resting

Time frame
Day 1
2

Postoperative static pain scores-Day 2

Pain score reported by patients when resting

Time frame
Day 2
3

Postoperative dynamic pain scores-Day 1

Pain score reported by patients when mobilizing or deep coughing

Time frame
Day 1
4

Postoperative dynamic pain scores-Day 2

Pain score reported by patients when mobilizing or deep coughing

Time frame
Day 2

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Taichung Veterans General Hospital

Lead sponsor

Source ClinicalTrials.gov
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