About this trial
This study uses number and size of ovarian follicles on the day of ovulation trigger as key determinants for oocytes yield to optimize outcomes in IVF and ICSI Protocols
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
women aged 18 to 35 years undergoing ICSI.
at least four follicles above 15 mm in diameter on the day of trigger
Downregulation using either GNRH antagonist or agonist protocol
Provision of written ,informed consent
Disqualifiers
anticipated poor responder, according to Bologna criteria
cycle canceled prior to retrieval or without trigger administration
Oocyte cryoperservation cycles or natural IVF cycles
presence of ovarian pathology affecting the follicular assessment (endometriosis,cysts )
Trial population
Female participants aged 18 to 35 years undergoing ICSI
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Total number of oocytes retrieved per participant during an ICSI cycle
The total number of oocytes retrieved will be recorded for each participant. Follicular number and mean follicular diameter will be measured by transvaginal ultrasound during ovarian stimulation, and their association with oocyte yield will be analyzed to determine minimum predictive thresholds for successful oocyte retrieval.
Secondary outcomes
Oocyte yield stratified by follicle size category and age group
The total number of oocytes retrieved per participant will be recorded and analyzed according to follicle size categories on the day of ovulation trigger. Participants will be stratified into predefined age groups (18-29 years and 30-35 years), and oocyte yield per follicle size category will be compared between age groups.
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options: