Establishing a Minimum Predictive Threshold Follicular Size and Oocyte Retrieval in ICSI Cycle

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-35
SponsorAssiut University

About this trial

This study uses number and size of ovarian follicles on the day of ovulation trigger as key determinants for oocytes yield to optimize outcomes in IVF and ICSI Protocols

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

women aged 18 to 35 years undergoing ICSI.

at least four follicles above 15 mm in diameter on the day of trigger

Downregulation using either GNRH antagonist or agonist protocol

Provision of written ,informed consent

Disqualifiers

anticipated poor responder, according to Bologna criteria

cycle canceled prior to retrieval or without trigger administration

Oocyte cryoperservation cycles or natural IVF cycles

presence of ovarian pathology affecting the follicular assessment (endometriosis,cysts )

Trial population

Female participants aged 18 to 35 years undergoing ICSI

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

60 Participants
are grouped into 1 trial group
Group A: ICSI observational Cohort

Trial outcomes

Primary outcomes

1

Total number of oocytes retrieved per participant during an ICSI cycle

The total number of oocytes retrieved will be recorded for each participant. Follicular number and mean follicular diameter will be measured by transvaginal ultrasound during ovarian stimulation, and their association with oocyte yield will be analyzed to determine minimum predictive thresholds for successful oocyte retrieval.

Time frame
From the start of controlled ovarian stimulation until the day of oocyte retrieval, assessed at oocyte retrieval (approximately 10-14 days after stimulation initiation and 34-36 hours after ovulation trigger).

Secondary outcomes

1

Oocyte yield stratified by follicle size category and age group

The total number of oocytes retrieved per participant will be recorded and analyzed according to follicle size categories on the day of ovulation trigger. Participants will be stratified into predefined age groups (18-29 years and 30-35 years), and oocyte yield per follicle size category will be compared between age groups.

Time frame
From the start of controlled ovarian stimulation until the day of oocyte retrieval, assessed at oocyte retrieval (approximately 10-14 days after stimulation initiation and 34-36 hours after ovulation trigger).

Other outcomes

Sponsors and contacts

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