The goal of this observational study is to better understand cognitive and affective processes involved in depression, in particular how individuals estimate their perception of control over events in their environment, as well as related processes such as memory and decision-making. The study also aims to investigate how these processes are affected by antidepressant treatment and how depressive symptoms evolve over time, as well as whether specific peripheral markers (including hormones) are associated with treatment effects.
Affiliated with a social security or national health insurance system, or entitled to such coverage.
Male or female, aged 18 to 55 years.
Fluent in spoken and written French.
Normal or corrected-to-normal vision.
History of a major depressive episode within the past 3 years.
Use of antidepressants, mood stabilizers, or antipsychotic medication within the past 3 years.
Diagnosis of a neurological or psychiatric disorder affecting central nervous system function (including bipolar disorder, schizophrenia, or other psychotic disorders according to DSM-5 criteria).
Pregnancy or breastfeeding (self-reported).
Hôpital le Vinatier
Lead sponsor
INSERM U1028
Collaborator